Mr. Jewell.

Abstract

prohibition be not quickly rescinded, there ought to be an aggregate meeting of the Profession to take the matter into consideration, and to agree to a petition for presentation to his Majesty upon the subject. DR. SIGMOND.To the Editor of THE LANCET. SIR,—I beg you will do me the justice to state, that I most distinctly disavow all connexion with the house to which your correspondent " Chirurgus" alludes, and that if my name has been employed in the way he states, it is a most shameful and

Integrating Biomaterials and Immunology to Improve Vaccines Against Infectious Diseases

“…Moreover, biomaterials allow the co-delivery of both antigen and molecular adjuvants to the same immune cells or tissues, which is important in potent activation of specific types of immune responses. 17,19 This feature has a distinct advantage compared to the delivery of soluble antigens and adjuvants in conventional soluble vaccines. Not surprisingly, a variety of biomaterials have been developed and tested for infectious disease vaccination.…”

“…Biomaterials also offer other key advantages that can be leveraged for vaccines, including co-encapsulation of antigen and immune-stimulatory agents, protection of cargo from enzymatic degradation, targeting of specific immune cells, and control over vaccine release kinetics. [17][18][19][20] Together, these features enable more precise control over immune processing of vaccines on both physiological and cellular levels, while potentially reducing toxicity compared to conventional vaccines. Owing to this potential, many biomaterials -including polymers, lipid, self-assembled proteins, and inorganic materials -are being explored for vaccines against numerous infectious diseases, though the majority of this work is thus far primarily in pre-clinical animal models.…”

New aromatic silicon‐containing polyamides

“…Thermogravimetric analyses (TGA) of the films were run in static air at 2"Clmin. with equipment and procedures described by Jewel1 (12). RESULTS…”