MR imaging of multiple myeloma patients with bone-marrow transplants

Abstract

MR has the potential to be a useful routine examination with T1-weighted and TIR sequences of selected areas, and without the use of contrast enhancement. However, further longitudinal studies are necessary in order to evaluate its possible predictive value.

Problems monitoring response in multiple myeloma

“…After bone marrow transplantation, bone marrow generally has a high signal on T1 weighted images but focal residual deposits are frequent [68]. The prognostic significance of these abnormalities is uncertain as patients with these residual abnormalities did not have a poorer outcome than those with normal post transplantation MRI scans [69].…”

Multiple myeloma

“…After bone marrow transplantation, bone marrow generally has a high signal on T1-weighted images but focal residual deposits are frequent [45]. The prognostic significance of these abnormalities is uncertain as patients with these residual abnormalities did not have a poorer outcome than those with normal post-transplantation MRI scans [46].…”