MR imaging of gallbladder carcinoma

Rossmann,; Friedman, AC; Radecki, PD; Df, Caroline

doi:10.2214/ajr.148.1.143

Cited by 21 publications

(6 citation statements)

References 4 publications

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“…There have been many reports of CT and MRI findings in gallbladder diseases [6][7][8][9][10][11][12]. To our knowledge, there have been no reports of the multiple-layer patterns of the gallbladder revealed by CT and MRI.…”

Section: Discussionmentioning

confidence: 98%

Endoscopic ultrasonography for demonstrating loss of multiple-layer pattern of the thickened gallbladder wall in the preoperative diagnosis of gallbladder cancer

et al. 1997

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The purpose of this study was to elucidate the roles of endoscopic ultrasonography (EUS), conventional US, CT, and MRI in differential diagnosis of gallbladder wall thickening. We scrutinized images for the presence of the multiple-layer patterns of the thickened gallbladder walls during preoperative images (EUS, n = 22; US, n = 23; CT, n = 20; MRI, n = 15) and retrospectively correlated them with surgical results in 25 patients. The pathological diagnoses included 7 gallbladder cancers, 9 cases of chronic cholecystitis, 5 cases of xanthogranulomatous cholecystitis, and 4 cases of adenomyomatosis. Multiple-layer patterns of gallbladder wall were observed in patients with inflammatory and benign diseases by US, EUS, CT, and MRI. This pattern was demonstrated by EUS more efficiently compared with other means of imaging. All subjects with loss of multiple layers were finally diagnosed by use of EUS as having gallbladder cancer at surgery. Loss of multiple-layer patterns of the gallbladder wall demonstrated by EUS was the most specific finding in diagnosing gallbladder cancer.

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Section: Discussionmentioning

confidence: 98%

Endoscopic ultrasonography for demonstrating loss of multiple-layer pattern of the thickened gallbladder wall in the preoperative diagnosis of gallbladder cancer

et al. 1997

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“…CT may more readily depict subtle extension of the tumor beyond the wall of the gallbladder (Fig 16b). MR imaging demonstrates prolongation of the T1 and T2 relaxation times in gallbladder carcinoma (53,54). Ill-defined early enhancement is a typical appearance of these tumors at dynamic gadolinium-enhanced MR imaging (Fig 18) (52).…”

Section: Radiologic Features Radiologic Evaluation Of the Primary Tumormentioning

confidence: 99%

Gallbladder Carcinoma: Radiologic-Pathologic Correlation

Levy¹,

Murakata²,

Rohrmann³

2001

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Primary carcinoma of the gallbladder is an uncommon, aggressive malignancy that affects women more frequently than men. Older age groups are most often affected, and coexisting gallstones are present in the vast majority of cases. The symptoms at presentation are vague and are most often related to adjacent organ invasion. Therefore, despite advances in cross-sectional imaging, early-stage tumors are not often encountered. Imaging studies may reveal a mass replacing the normal gallbladder, diffuse or focal thickening of the gallbladder wall, or a polypoid mass within the gallbladder lumen. Adjacent organ invasion, most commonly involving the liver, is typically present at diagnosis, as is biliary obstruction. Periportal and peripancreatic lymphadenopathy, hematogenous metastases, and peritoneal metastases may also be seen. The vast majority of gallbladder carcinomas are adenocarcinomas. Because most patients present with advanced disease, the prognosis is poor, with a reported 5-year survival rate of less than 5% in most large series. The radiologic differential diagnosis includes the more frequently encountered inflammatory conditions of the gallbladder, xanthogranulomatous cholecystitis, adenomyomatosis, other hepatobiliary malignancies, and metastatic disease.

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“…Computed tomography (CT) and ultrasound have been used to demonstrate the primary lesion and local spread of gallbladder carcinoma; however, these image modalities are limited for detecting lesions, as well as vascular and biliary invasion (11–16). Several recent studies describe the usefulness of magnetic resonance (MR) imaging in the evaluation of gallbladder carcinoma, but there has not been enough attention to local tumor spread into adjacent organs, major visceral vessels, and bile ducts (17–21). Recent MR techniques, such as MR cholangiography (MRC) and MR angiography (MRA), have improved the evaluation of bile ducts and vascular structures.…”

mentioning

confidence: 99%

Preoperative evaluation of gallbladder carcinoma: Efficacy of combined use of MR imaging, MR cholangiography, and contrast‐enhanced dual‐phase three‐dimensional MR angiography

Kim¹,

Eun²,

Kim³

et al. 2002

Magnetic Resonance Imaging

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Purpose:To determine the efficacy of the combined use of magnetic resonance (MR) imaging, MR cholangiography (MRC), and MR angiography (MRA) in the preoperative evaluation of gallbladder carcinoma. Materials and Methods:During a 20-month period, 41 patients with proven gallbladder carcinomas were referred for MR examination, including MR imaging, MRC, and gadolinium-enhanced dual-phase MRA to determine the operability of their gallbladder carcinoma. Eighteen patients who underwent surgery within six days of the MR examination were included in this study. All MR images were analyzed in order to assess bile duct invasion, vascular invasion, hepatic invasion or metastasis, lymph node metastasis, and invasion into adjacent organs.Results: Surgical and histopathologic findings revealed hepatic invasion in nine patients, bile duct invasion in nine, vascular invasion in three, and lymph node metastasis in 10. The sensitivity and specificity of MR examination were, respectively, 100% and 89% for bile duct invasion, 100% and 87% for vascular invasion, 67% and 89% for hepatic invasion, and 56% and 89% for lymph node metastasis. Conclusion:The "all-in-one" MR protocol, including MR imaging, MRC, and MRA, can be an effective diagnostic method in the preoperative work-up for gallbladder carcinoma.

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MR imaging of gallbladder carcinoma

Cited by 21 publications

References 4 publications

Endoscopic ultrasonography for demonstrating loss of multiple-layer pattern of the thickened gallbladder wall in the preoperative diagnosis of gallbladder cancer

Endoscopic ultrasonography for demonstrating loss of multiple-layer pattern of the thickened gallbladder wall in the preoperative diagnosis of gallbladder cancer

Gallbladder Carcinoma: Radiologic-Pathologic Correlation

Preoperative evaluation of gallbladder carcinoma: Efficacy of combined use of MR imaging, MR cholangiography, and contrast‐enhanced dual‐phase three‐dimensional MR angiography

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