MR imaging of calcified intracranial lesions.

“…The above findings correlated with literature. 10,11,12 Ependymoma In this study there was one case of ependymoma (2%), which correlates with the reported literature. 13,14 According to Gregory B Nazar et al 14 ependymomas are the third most common paediatric brain tumour and two-third are infratentorial in location.…”

Section: Oligodendrogliomasupporting

confidence: 91%

Mri Evaluation of Supratentorial Tumours

Patil¹,

Mahesh²,

Govindaraju³

2016

jemds

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Brain tumours represents 1.7% of all cancers and contributes 1.8% of all cancer deaths. Of all the brain tumours 80% are supratentorial. 1 Magnetic Resonance Imaging is an important modality, having higher sensitivity for detecting intracranial pathology. Multiplanar imaging is possible with MRI which helps in detection, localization and characterization of the lesion. The MRI examination has helped in early diagnosis, accurate localization of the tumour with prompt initiation of appropriate medical or surgical therapy. Recent advances like Magnetic Resonance (MR) spectroscopy, MR fluoroscopy with stereotactic guided biopsy have revolutionized the role of MRI in study of intracranial tumours. AIMS AND OBJECTIVESThe objective of the present study is to assess diagnostic ability of MRI in characterizing various supratentorial tumours using T1 and T2 weighted and contrast enhanced image. MATERIALS AND METHODSThe present study was conducted in the Department of Radio-diagnosis, Basaveshwar Teaching and General Hospital attached to Mahadevappa Rampure Medical College, Gulbarga, during the period of Oct 2014 to Oct 2015. Source of dataAll clinically suspected supratentorial brain tumour cases undergoing MRI at Basaveshwar Teaching and General Hospital attached to Mahadevappa Rampure Medical College, Gulbarga, are taken. Inclusion CriteriaCases referred for MRI with clinically suspected supratentorial brain tumours. Exclusion CriteriaAll patients having cardiac pace makers, prosthetic heart valves or any metallic orthopaedic implants. Supratentorial pathology due to infections Trauma or cerebrovascular accidents will be excluded. RESULTSThe present study was conducted in the Department of Radio-diagnosis. BTGH attached to MR Medical College Gulbarga patients were studied and the observations and findings were noted as below. In the present study, Majority of the patients belonged to the age group of 11 to 20 years, 23 patients were males and 27 were females, males majority had glioma of low-grade variety. In females glioma followed by pituitary adenoma. Headache and vomiting most common presentations. Majority of the supratentorial tumors had intra-axial location. Mass of effect and hydrocephalus is present in majority of patients.

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“…Melanoma and neurofibromatosis can also be differentiated from Mn deposits from knowledge of the site and symmetry of the signals. The signal intensity of calcification can be shown as diminished, null effect, or increased in T1-weighted MRI [26][27][28][29][30][31][32] . Increased signal is only seen with low concentration of calcium, and the signal intensity progressively decreases as the calcium concentrations increase above 30-40% by weight 27) .…”

Section: Mn-induced High Signals Should Be Differentiated From High Smentioning

confidence: 99%

High Signal Intensities on T1-Weighted MRI as a Biomarker of Exposure to Manganese.

Kim

2004

INDUSTRIAL HEALTH

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Increased signal in T1-weighted images was observed in the experimental manganese (Mn) poisoning of the non-human primate and a patient with Mn neurointoxication. However, our study showed that the increased signals in magnetic resonance images (MRI) were highly prevalent (41.6%) in Mn-exposed workers. Especially 73.5% of the welders showed increased signal intensities. Blood Mn concentration correlated with pallidal index. These changes in MRI tend to disappear following the withdrawal from the source of Mn accumulation, despite permanent neurological damage. Thus increased signal intensities on a T1-weighted image reflect exposure to Mn, but not necessarily manganism. Our study also showed that the concentration of Mn required to produce increased signal intensities on MRI is much lower than the threshold necessary to result in overt clinical signs of manganism. Increased signal intensities in the globus pallidus were determined by Mn accumulation in the animal experiment. All these results strongly suggest that signal intensities in T1-weighted MRI reflect a target site dose in a biologically-based dose-response model. At which increase of signal intensity, the progression of manganism from Mn exposure occurs, however, remains to be solved.

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MR imaging of calcified intracranial lesions.

Cited by 94 publications

References 0 publications

Magnetic resonance imaging of experimental mumps meningoencephalitis in suckling hamsters

Magnetic resonance imaging of experimental mumps meningoencephalitis in suckling hamsters

Mri Evaluation of Supratentorial Tumours

High Signal Intensities on T1-Weighted MRI as a Biomarker of Exposure to Manganese.

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