MR imaging in the diagnosis of a retroperitoneal schwannoma

Cretella, Joseph P.; Rafal, Richard B.; McCarron, James P.; Markísz, John A.

doi:10.1016/0895-6111(94)90031-0

Cited by 8 publications

(3 citation statements)

References 12 publications

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“…MRI was helpful because it has a better definition, multiplanar capabilities, and the possibility to differentiate the nature of the tumor, such as solid tissue, fibrous tissue, simple or atypical fluid, and blood [14] . It confirmed the presence of a solid, homogeneous mass, and showed its relation to adjacent structures in greater detail [6,15] . No invasive process was revealed and the margins were still regular, convincing us that the mass was benign in nature [16] .…”

Section: Discussionmentioning

confidence: 71%

Benign retroperitoneal schwannoma presenting as colitis: A case report

Fass¹

2007

WJG

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We report a case of a patient presenting with clinical, radiological and endoscopic features of colitis due to a compressive left para-aortic mass. Total open surgical excision was performed, which resulted in complete resolution of colitis. Histopathology and immunohistochemistry revealed benign retroperitoneal schwannoma. These neural sheath tumors rarely occur in the retroperitoneum. They are usually asymptomatic but as they enlarge they may compress adjacent structures, which leads to a wide spectrum of non-specific symptoms, including lumbar pain, headache, secondary hypertension, abdominal pain and renal colicky pain. CT and MR findings show characteristic features, but none are specific. Schwannoma can be isolated sporadic lesions, or associated with schwannomatosis or neurofibromatosis type II (NF2). Although they vary in biological and clinical behavior, their presence is, in nearly every case, due to alterations or absence of the NF2 gene, which is involved in the growth regulation of Schwann cells. Both conditions were excluded by thorough mutation analysis. Diagnosis is based on histopathological examination and immunohistochemistry. Total excision is therapeutic and has a good prognosis. Schwannomatosis and NF2 should be excluded through clinical diagnostic criteria. Genetic testing of NF2 is probably not justified in the presence of a solitary retroperitoneal schwannoma.

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Section: Discussionmentioning

confidence: 71%

Benign retroperitoneal schwannoma presenting as colitis: A case report

Fass¹

2007

WJG

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“…4-6, 9-11). 4,19 However it is incapable of reliably distinguishing between benign and malignant tumours. Schwannomas characteristically possess low signal intensity on T1-WI similar to muscle (Fig.…”

Section: 7)mentioning

confidence: 99%

Retroperitoneal Giant Schwannomas: Report on Two Cases and Review of the Literature

Schindler¹,

Dixon²,

Case

2002

J Orthop Surg (Hong Kong)

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The occurrence of massive retroperitoneal schwannomas is extremely rare and their presence may only be expressed by insidious onset of non-specific and misleading symptoms with a predominance of lower back pain. MRI scan as the imaging procedure of choice will demonstrate the tumour location and its relation to the surrounding structures, but due to heterogeneity and degeneration in some tumours, it may mimic malignancy. Hence tissue sampling through needle biopsies are essential to verify the diagnosis prior to surgery. Tumour excision in toto is considered the treatment of choice, but it can be hazardous especially if the tumour is adherent to the presacral venous plexus. Severe bleeding complications due to the damage of venous structures have to be encountered, and establishing lasting haemostasis may pose considerable difficulties. Hence surgery should be attempted with full precautions, and preoperative counseling of the patient. If malignancy can safely be excluded, laparoscopic piecemeal excision should be considered as an alternative treatment as recurrence is unlikely. Definition of the originating nerve might not always be possible and a minor degree of neurological impairment has therefore to be anticipated.

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“…CT and ultrasound imaging features of most retroperitoneal schwannomas are nonspecific, which makes it difficult to differentiate schwannomas from other soft tissue tumors. The MR appearance of retroperitoneal schwannoma, which is similar to peripheral schwannomas, has been described as isointense with muscle on T1-weighted images and hyperintense on T2-weighted images [5,6]. MRI reveals a more precise origin and location of the tumor, presence of invasion, and involvement of the surrounding organs than either CT or ultrasound.…”

Section: Discussionmentioning

confidence: 98%

Solitary Benign Schwannoma of the Psoas Muscle: A Case Report

Lin

et al. 2008

Chir Gastroenterol

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Background: Schwannomas of the retroperitoneum may grow very large prior to diagnosis. Neuropathy of the lower extremities also may result. Case Report: A retroperitoneal tumor was found incidentally by computed tomography which was originally performed to evaluate a hepatic tumor in a 57-year-old male. Schwannoma without invasion of surrounding tissue in the right psoas muscle was diagnosed with magnetic resonance imaging. Exploratory laparotomy with wide resection of the hepatic tumor and enucleation of the schwannoma was performed. Conclusion: Enucleation is an efficient treatment for schwannomas in the psoas muscle. Prognosis is good since postoperative recurrence is unusual.

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MR imaging in the diagnosis of a retroperitoneal schwannoma

Cited by 8 publications

References 12 publications

Benign retroperitoneal schwannoma presenting as colitis: A case report

Benign retroperitoneal schwannoma presenting as colitis: A case report

Retroperitoneal Giant Schwannomas: Report on Two Cases and Review of the Literature

Solitary Benign Schwannoma of the Psoas Muscle: A Case Report

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