MR Imaging Findings of the Uveal Schwannoma

Jian, Xian; Xu, Xinglian; Wang, Z.; Yang, Bentao; Li, B.; Man, Frances S. de; Chen, Q.; Shi, Jiahai; Zhang, Y.

doi:10.3174/ajnr.a1467

Cited by 17 publications

(10 citation statements)

References 21 publications

(80 reference statements)

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“…Although non-contrast MR imaging findings are non-specific, they may offer some advantage in the differentiation of orbital cavernous haemangiomas by demonstrating marked hyperintensity signal to muscle with internal septations on T2-weighted imaging, a hypointense circumferential rim corresponding to the fibrous pseudocapsule, and chemical shift artefact in the frequency-encoded direction secondary to high water content within the lesion surrounded by orbital fat [ 5 , 7 , 17 ]. Orbital schwannoma is isointense with respect to the extraocular muscle on T1-weighted images and mildly hyperintense on T2-weighted images [ 6 , 18 ]. Orbital schwannomas may undergo cavitary change, which appears as a cystic mass with straw-coloured fluid on gross pathological examination and looks homogeneously hypointense to muscle on T1-weighted images and hyperintense on T2-weighted images [ 8 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of MR imaging findings differentiating cavernous haemangiomas from schwannomas in the orbit

et al. 2010

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ObjectiveIt is important to distinguish between orbital cavernous haemangioma and schwannoma because the treatments of choice for the two tumours are different. The aim was to evaluate MR imaging findings distinguishing the two tumours.MethodsMagnetic resonance imaging including T1- and T2-weighted imaging and contrast-enhanced MR imaging was performed in 43 patients with cavernous haemangiomas and 16 patients with schwannomas confirmed by pathology. Location, configuration, margins, signal intensity, homogeneity and enhancement pattern of the tumour were retrospectively evaluated.ResultsThere was a significant difference between cavernous haemangiomas and schwannomas regarding the location, configuration and margins of the mass, signal intensity and homogeneity on T1- and T2-weighted imaging, the spread pattern of contrast enhancement, the enhancement pattern and the type of time–intensity curve (P < 0.05). Markedly homogeneous hyperintensity signal on T2-weighted imaging and the spread pattern of the contrast enhancement favoured cavernous haemangioma rather than schwannoma (P < 0.01).ConclusionCavernous haemangiomas and schwannomas have different MR imaging features that could be helpful in the differentiation between the tumours. The spread pattern of the contrast enhancement on dynamic contrast-enhanced MR imaging is the most reliable finding distinguishing cavernous haemangiomas from schwannomas.

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Section: Discussionmentioning

confidence: 99%

“…Compared with orbital cavernous haemangiomas, no “progressive” enhancement pattern was found in orbital schwannomas [ 12 , 18 ]. Therefore, our results and the literature showed that the “progressive” enhancement pattern will be the most reliable finding in distinguishing orbital cavernous haemangiomas from schwannomas.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of MR imaging findings differentiating cavernous haemangiomas from schwannomas in the orbit

et al. 2010

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“…Similarly, leiomyoma and schwannoma of ciliary body may be indistinguishable from ANPCE by clinical or imaging findings but may also be treated with local resection, like ANPCE. 12,20 The most appropriate management for ANPCE is generally local tumor resection only, rather than enucleation, if ANPCE is detected clinically at a relatively early stage.…”

Section: Discussionmentioning

confidence: 99%

“…Other main considerations in the differential diagnosis are medulloepithelioma, adenoma, or adenocarcinoma of the ciliary pigment epithelium, leiomyoma, schwannoma, metastatic carcinoma, and granuloma. [2][3][4][5][6][12][13][14]16,19,20 Unlike ANPCE, many of these lesions require enucleation. Medulloepithelioma, a congenital tumor with its onset in the first decade of life and often associated with lens coloboma, iris neovascularization, and signs of persistent primary vitreous, 16 can be differentiated readily by clinical findings.…”

Section: Discussionmentioning

confidence: 99%

MR Imaging of Adenomas of the Nonpigmented Ciliary Epithelium of the Eye

Jian¹,

Xu²,

Wang³

et al. 2009

AJNR Am J Neuroradiol

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“…So compared with orbital cavernous hemangioma, no progressive enhancement pattern was seen in orbital schwannoma. So progressive enhancement pattern was one of the better findings to differentiate both the tumors [17,27]. On the imaging study, most of the cavernous hemangiomas were separated but compressed the optic nerve and extraocular muscles and schwannoma was usually seen overlapping the optic nerve.…”

Section: Orbital Hemangiomamentioning

confidence: 99%

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

Akter¹,

Hasan²,

Sana³

et al. 2017

J Pain Relief

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Purpose: To valuate four-quadrant location method in diagnosis and differential diagnosis of the orbital tumor by comparison study combining CT and MRI with pathology. Materials and methods:Data of 87 patients (44 female and 43 males), aged 1 to 84 years were recruited in this study, including the computed tomography(CT), Magnetic resonance imaging (MRI), and histopathology diagnosis. All orbital tumors were verified radiologically and pathologically in the Hospital of Jinggangshan University from Sep-2008 to April-2016 patients underwent CT scanning (31 Conventional CT and 18 dynamic contrast enhancements CT) and 38 patients underwent MR Imaging (35 dynamic contrast enhancement MRI and 3 conventional MRI). The clinical data were retrieved from the medical record. We classified the orbital region according to four-quadrant and eight-space (FQES) division and traditional muscleconal division with center point of optic nerve. Results:Among the 87 cases of the orbital tumors, 70 cases (80.45%) were orbital benign tumors and 17 cases (19.54%) were malignant tumors. Regarding the location of the orbit, 41 lesions (47.12%) were in superolateral, 18 lesions (20.68%) were in inferolateral, 16 lesions (18.39%) were in inferomedial, 8 lesions (9.19%) were in superomedial, 3 lesions (3.44%) were in globe, 1 lesion (1.14%) was in optic nerve. The most common tumors are hemangiomas (total 36 cases: 12 in inferolateral, 8 in inferomedial, 9 in superolateral, 7 in superomedial) and 9 cases of pleomorphic adenoma were in superolateral, 9 cases of dermoid cyst ( 7 in superolateral and in 2 inferomedial), 5 cases of inflammatory pseudotumor (4 in superolateral and 1 in inferomedial), 7 cases of lymphoma (3 in superolateral, 2 in inferolateral and 2 in inferomedial ), 3 cases of adenoid cystic carcinoma in superolateral, 3 caese solitary fibrous tumor ( 2 in suprolateral and 1 in inferomedial), 3 cases lipoma (1 in superomedial, 1 in superolateral and 1 in inferolateral), 2 cases choroidal melanoma were in globe, 1 case of metastasis in superolateral, 1 case of meningioma in optic nerve, 1 case of malignant melanoma was in superolateral. The orbital tumors appeared in orbit with mostly regular, oval and rounds shape, well defined margin. The size ranged from 0.8 mm × 4.5 cm to 4.5 cm × 2.0 cm. The CT revealed iso-density in 22, slightly high-density in 15, mixed density in 6, low density in 5 and high density in 1 lesion. Among them, 18 were contrast enhancements. On T1WI image, the MRI revealed low signal intensity in 23 cases, slightly low signal in 4 cases, iso signal intensity in 7 case, high signal intensity in 3 cases, mixed signal intensity in 1 case on T2WI, it revealed high signal intensity in 23 cases, slightly high intensity in 7 cases, low signal intensity in 4 cases, iso signal intensity in 3 cases, mixed signal intensity in 1 case. Among them, 35 contrast enhancement MRI and 3 were non contrast MRI. Benign tumor was diagnosed in 70 patients, of them 34 were male and 36 were female, and the mean age was 45.19 ...

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MR Imaging Findings of the Uveal Schwannoma

Abstract: BACKGROUND AND PURPOSE:Uveal schwannoma is a rare benign neoplastic proliferation of pure Schwann cells. The purpose of this study was to describe MR imaging features of uveal schwannoma.

Cited by 17 publications

References 21 publications

Evaluation of MR imaging findings differentiating cavernous haemangiomas from schwannomas in the orbit

Evaluation of MR imaging findings differentiating cavernous haemangiomas from schwannomas in the orbit

MR Imaging of Adenomas of the Nonpigmented Ciliary Epithelium of the Eye

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

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