MR findings of ovarian tumours with cystic components.

Kinoshita, Toshibumi; Ishii, Kazunari; Naganuma, Hiroko; Higashiiwai, Hisashi

doi:10.1259/bjr.73.867.10817054

Cited by 22 publications

(9 citation statements)

References 8 publications

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“…It has been reported in numerous publications that Gd chelates improve sensitivity, specificity and diagnostic accuracy of MR procedures [5,21,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60]. Indications for their use include the evaluation of tumoral, traumatic and infectious disease processes.…”

Section: Indicationsmentioning

confidence: 99%

“…The combined use of Gd chelates and breathhold imaging (increased tumour-to-parenchyma contrast ratio) results in better tumour detection in most organs, as compared with unenhanced MR imaging. Most MR information for characterizing liver [44,45] and renal [53,54] tumours, and in the pretherapeutic assessment of uterine [55], ovarian [56], bladder and prostate tumours [57,58]. Controversies remain concerning the best contrast agent for MR imaging of the liver, either for detection or characterization: extracellular compounds; superparamagnetic particles; manganese or gadobenate dimeglumine which has a nonspecific extracellular phase followed by specific uptake by functioning hepatocytes prior to its excretion into the bile.…”

Section: Abdomen and Pelvismentioning

confidence: 99%

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Currently used non-specific extracellular MR contrast media

2003

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Magnetic resonance contrast agents have demonstrated their clinical usefulness in a variety of organs for improved detection of various neoplastic, inflammatory and functional abnormalities. Gadolinium chelates are the most widely used. They are extracellular, non-specific contrast agents. Their use in many clinical indications is justified because, in conjunction with improved imaging techniques, these safe and image-enhancing contrast agents add morphologic and functional information compared with unenhanced MR images. This article describes the commercially available compounds, and summarizes their approval status on the international market regarding indications and doses. Their mechanisms of action, biodistributions, toxicities and tolerance profiles in normal and high-risk patient populations are described. Additionally, this article reviews the specific recommendations by the manufacturers for patients at risk. Finally, their main clinical applications are reviewed.

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Section: Indicationsmentioning

confidence: 99%

Section: Abdomen and Pelvismentioning

confidence: 99%

Currently used non-specific extracellular MR contrast media

2003

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“…MRI plays an important role in the diagnosis of gynaecological adnexial lesions [1][2][3][4]. It provides useful information for the characterisation of various ovarian, uterine and tubal masses.…”

mentioning

confidence: 99%

Diffusion-weighted imaging of solid or predominantly solid gynaecological adnexial masses: is it useful in the differential diagnosis?

Bakir¹,

Bakan²,

Tunacı³

et al. 2011

BJR

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Objectives: This study investigated whether diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values provide specific information that allows the diagnosis of solid or predominantly solid gynaecological adnexial lesions, especially whether they can discriminate benign and malignant lesions. Methods: DWI was performed in 37 patients with histologically proven solid or predominantly solid adnexial lesions (22 malignant and 15 benign neoplasms). The lesions in our data set were divided into two groups, all adnexial lesions or lesions of ovarian origin, for evaluation. The areas of the highest signal intensity on DWI (b5800 s mm 22) and the lowest ADC values within the lesions were evaluated. Results: On DWI, high signal intensity was observed more often in malignant than in benign lesions (p,0.0001). There was no significant difference between the ADC values of the malignant and benign lesions in either the adnexial (0.88¡0.16 vs 0.84¡0.42; p50.96) or the ovarian (0.85¡0.14 vs 1.05¡0.2; p50.133) lesions. When signal intensities on DWI were compared, however, malignant lesions had higher values than the benign lesions in both the adnexial (0.69¡0.21 vs 0.29¡0.13; p,0.0001) and the ovarian lesions (0.75¡0.14 vs 0.37¡0.24; p50.003). Conclusion: On DWI, high signal intensity was observed more frequently with the malignant lesions.

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“…9 It plays an important role in the diagnosis of gynaecological adnexal lesions. 10 Some morphological and signal intensity features of the lesions on MRI are very important for the differential diagnosis, 11 but this information may sometimes be non-specific. Many studies have looked at the utility of DWI in the differential diagnosis of benign and malignant gynaecological lesions.…”

Section: Discussionmentioning

confidence: 99%