MR diagnosis of adenomyomatosis of the gallbladder and differentiation from gallbladder carcinoma: importance of showing Rokitansky-Aschoff sinuses.

Yoshimitsu, Kengo; Honda, Hiroshi; Jimi, Makiko; Kuroiwa, Toshiro; Hanada, K.; Irié, Hiroyuki; Tajima, Tsuyoshi; Tomita, Masaki; Chijiiwa, Kazuo; Shimada, Mitsuo; Masuda, Kouji

doi:10.2214/ajr.172.6.10350285

Cited by 93 publications

(42 citation statements)

References 7 publications

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“…A recently reported characteristic is the presence of nodules on the gallbladder wall, hypoechogenic on US or hypodense on CT, which are the first phase of parietal abscesses that subsequently transform into xanthogranulomas [60][61][62]. In MR, these nodules can be demonstrated by chemical displacement techniques that show a fall in signal in the opposite phase sequence due to the presence of intracytoplasmatic fat [63]. There has been a report [70] of a false positive FDG-PET scan in a case of xanthogranuloma to us cholecystitis.…”

Section: Proposals For the Differential Diagnosismentioning

confidence: 99%

Application of modern imaging methods in diagnosis of gallbladder cancer

Rodrı́guez-Fernández

Gómez-Río

Medina-Benítez

et al. 2006

Journal of Surgical Oncology

103

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The poor prognosis of gallbladder cancer (GBC) is related to its dissemination capacity and usually late diagnosis due to its non-specific clinical appearance. Recent improvements in hepatobiliary surgery have underlined the importance of an early specific diagnosis, which requires a multidisciplinary approach and, when possible, specialized equipment. The first step in an early diagnosis is to identify patients in the appropriate epidemiological setting (e.g., incidental finding, chronic cholecystitis) for the correct interpretation of test results. It is desirable to enhance the sensitivity of the initial ultrasound (US) examination by use of the appropriate technology in skilled specialist hands. When GBC is suggested by US findings, FDG-PET can be considered complementary to establish the benign/malignant nature of the lesion and to obtain a primary staging study. If GBC is confirmed, thin slice spiral CT can contribute valuable information on local spread. In this regard, recent hybrid PET-CT systems provide structural and functional information simultaneously and may offer early and accurate T, N, and M staging with an improved specificity.

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Section: Proposals For the Differential Diagnosismentioning

confidence: 99%

Application of modern imaging methods in diagnosis of gallbladder cancer

Rodrı́guez-Fernández

Gómez-Río

Medina-Benítez

et al. 2006

Journal of Surgical Oncology

103

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“…Adenomyomatosis of the gallbladder is a common disease that usually presents as a focal lesion or as a diffuse wall thickening of the gallbladder, and therefore differentiating it from gallbladder carcinoma is important [24]. The value of the Rokitansky-Aschoff sinuses in the diagnosis of adenomyomatosis has been suggested on transabdominal sonography, CT, and MR imaging [25][26][27].…”

Section: Benign Lesionsmentioning

confidence: 99%

Differential diagnosis of gallbladder cancer using positron emission tomography with fluorine‐18‐labeled fluoro‐deoxyglucose (FDG‐PET)

Koh

Taniguchi

Yamaguchi³

et al. 2003

Journal of Surgical Oncology

105

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“…The identification of the Rokitansky-Aschoff sinuses is the key factor in establishing a diagnosis of gallbladder adenomyomatosis. At present, magnetic resonance (MR) imaging is accepted as the most accurate modality in the delineation of Rokitansky-Aschoff sinuses (3)(4)(5). The ability of spiral computed tomography (CT) to depict these sinuses is limited due to insufficient spatial and contrast resolution (2,3 …”

Section: Introductionmentioning

confidence: 99%

“…The 'pearl necklace' or 'string of beads' sign is the hallmark of adenomyomatosis at MR imaging. It refers to small, rounded, high signal intensity foci within the thickened wall of the gallbladder on T2-weighted sequences, that correspond to bile filled Rokitansky-Aschoff sinuses (4,5). This sign is highly specific (92%) in diagnosing of gallbladder adenomyomatosis versus gallbladder cancer.…”

mentioning

confidence: 99%