MR Colonography Without Colonic Cleansing

Lauenstein, Thomas C.; Holtmann, Gerald; Schoenfelder, D.; Bosk, Silke; Ruehm, S. G.; Debatin, Jörg F.

doi:10.2214/ajr.177.4.1770823

Cited by 83 publications

(3 citation statements)

References 21 publications

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“…Pappalardo et al [19] showed that MRC was associated with similar diagnostic accuracy for diagnosing colonic endoluminal lesions compared with conventional colonoscopy. Lauenstein et al [20,21] indicated that barium-tagged MRC was promising for detecting all lesions more than 8 mm in diameter. Luboldt et al [22] found that MRC was promising for filtering out individuals with obvious colorectal mass lesions.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of magnetic resonance versus computed tomography colonography for colorectal cancer

Sun

Yang²,

Huang³

et al. 2018

Medicine

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Section: Discussionmentioning

confidence: 99%

Diagnostic value of magnetic resonance versus computed tomography colonography for colorectal cancer

Sun

Yang²,

Huang³

et al. 2018

Medicine

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“…Fecal tagging is a concept based on altering the signal intensity of stool by adding contrast modifying substances to regular meals such as barium sulfatecontaining contrast agent (33,(63)(64). This has been shown to decrease the signal intensity of stool in T1-weighted images because of the extended relaxation time.…”

Section: Dark-lumen Mrc With Fecal Taggingmentioning

confidence: 99%

“…Thus, fecal tagging may render stool virtually indistinguishable from the distending rectal enema on MR images. The fecal tagging based MRC was applied successfully in a volunteer study (63). However it has shown a poor diagnostic accuracy and poor acceptance in a patient study (64).…”

Section: Dark-lumen Mrc With Fecal Taggingmentioning

confidence: 99%

Clinical use of MRI: Virtual Dark-Lumen MR Colonography: Technique, Application and Accuracy

Ajaj¹

2012

An-Najah Univ J Res-B (Humanities)

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Conventional colonoscopy represents the gold standard for the detection of colorectal pathologies. However, due to its invasiveness and procedure-related discomfort, patient acceptance is somtimes poor. In the last few years, the use of MR Colonography has been shown to be an appropriate diagnostic tool for the detection of colorectal pathologies. Dark-lumen MR Colonography has been introduced. This technique is based on the acquisition of a T1-weighted sequence following the administration of a water-enema and the intravenous administration of paramagnetic contrast. This review article describes the underlying technique of dark-lumen MR Colonography, the process of data acquisition, image interpretation, as well as application and accuracy. Additionally, the benefits of this approach compared to conventional colonoscopy, new techniques to improve patient acceptance and diagnostic accuracy will be reviewed. Keywords: Conventional colonoscopy, virtual

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MR colonography: How does air compare to water for colonic distention?

Ajaj¹,

Lauenstein²,

Pelster³

et al. 2004

Magnetic Resonance Imaging

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Purpose:To prove the feasibility of air-distended magnetic resonance colonography (MRC) and compare it with waterbased distention. Materials and Methods:In five volunteers, the colon was imaged twice: once after distending the colon with air and a second time after distending the colon with water. A total of 50 patients, who had been referred to colonoscopy for a suspected colorectal pathology were randomized into water-distention (N ϭ 25) and air-distention (N ϭ 25) groups. A contrast-enhanced T1-weighted three-dimensional volume interpolated breath-hold (VIBE) sequence was collected. Comparative analysis was based on qualitative ratings of image quality and bowel distention, as well as contrast-to-noise ratio (CNR) measurements for the colonic wall with respect to the colonic lumen. In addition, patient acceptance was evaluated.Results: Inflammatory changes and colorectal masses were correctly identified on MRC in eight patients each. One 4-mm polyp identified at colonoscopy was missed on waterdistended MRC. There were no false positive findings. No significant differences were found between air-and waterdistention regarding discomfort levels and image quality. The presence of air in the colonic lumen was not associated with susceptibility artifacts. CNR of the contrast-enhanced colonic wall, as well as bowel distention, were superior on air-distended three-dimensional data sets. Conclusion:MRC can be performed using either water or air for colonic distention. Both techniques permit assessment of the colonic wall and identification of colorectal masses. While discomfort levels are similar for both agents, MRC with air provides higher CNR and better colonic distention. MAGNETIC RESONANCE (MR) colonography (MRC) has been shown to be an appropriate diagnostic tool for the detection of pathologies, including colorectal masses, diverticula, and inflammatory disease (1-4). Reliable assessment of the colon by means of MR imaging is predicated upon the fulfillment of two requirements: sufficient distention of the colonic lumen and sufficient contrast between the colonic lumen and pathologies arising from the colonic wall. Hence, the cleansed colon is filled either with liquid, such as tap water, with or without the addition of paramagnetic contrast (2,5,6), or gaseous agents, such as room air, CO 2 , and hyperpolarized helium (7-9). While initial experience was based on techniques rendering the colonic lumen bright, dark lumen MRC has recently been found to be advantageous (1,3).The fear of compromised image quality due to susceptibility effects at air/tissue interfaces has long favored the use of water or water-based solutions for colonic distention in MRC (6,10). With the availability of high performance gradients permitting data acquisition with very short echo times, the potential of relevant susceptibility effects is reduced. Accordingly, interest in the use of gaseous agents has grown. They avoid the risk of spillage and have been suggested to be associated with less discomfort compared to fluid (7,8).The purpos...

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MR Colonography Without Colonic Cleansing

Abstract: Fecal tagging obviates bowel cleansing and should, therefore, enhance patient acceptance for MR colonoscopy. Barium used as the tagging agent is promising because it is inexpensive, commercially available, and characterized by an excellent safety profile.

Cited by 83 publications

References 21 publications

Diagnostic value of magnetic resonance versus computed tomography colonography for colorectal cancer

Diagnostic value of magnetic resonance versus computed tomography colonography for colorectal cancer

Clinical use of MRI: Virtual Dark-Lumen MR Colonography: Technique, Application and Accuracy

MR colonography: How does air compare to water for colonic distention?

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