Mpox and pregnancy: A neglected disease and its impact on perinatal health

Velázquez-Cervantes, M.A.; Ulloa-Aguilar, J.M.; León-Juárez, Moisés

doi:10.1016/j.rceng.2022.09.002

Cited by 3 publications

(3 citation statements)

References 35 publications

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“…Those at higher risk of being infected with the virus or death may include pregnant women, children, and individuals who are immunocompromised. [11] The emergence of the rash can be seen as the first indication of infection. Further, MPX signs and/or symptoms frequently start in regions of the head and advance to the patient's arms, legs, palms, and soles.…”

Section: What Are the Signs And/or Symptoms Of Human Monkeypox Virus ...mentioning

confidence: 99%

Demographic, transmission, and clinical characteristics associated with human monkeypox infection, October 2022: a systematic analysis for World Health Organization database and brief review

Yon¹

2022

Life Cycle

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The monkeypox (MPX) is an unusual viral disease which, until recently, has rarely been detected outside of Africa. A total of 71,237 confirmed cases of MPX, as of October 6th, 2022, had been discovered in 109 countries in the matter of months. The risk factors of MPX are men who have sex with the same gender (prevalence 90.0%, 95% CI, 89.5 to 90.4), sexual exposure to sex partners with MPX (prevalence 87.3%, 95% CI 6.7 to 87.8), human immunodeficiency virus-positive individuals (prevalence 49.1%, 95% CI, 48.4 to 49.8), people who have travel history to Africa (prevalence 16.9%, 95% CI, 16.2 to 17.7), hospitalization (prevalence 7.3%, 95% CI 7.0 to 7.6), health workers (prevalence 3.2%, 95% CI 2.9 to 3.5), admission to intensive care unit (prevalence 0.18%, 95% CI 0.11 to 0.28), and death (prevalence 0.03%, 95% CI 0.02 to 0.06). According to an international cohort of 60,510 individuals, the MPX can result in rash (all types; 83.6%, n=21,472), fever (57.8%, n=14,842), rash on the whole body (49.6%, n=12,730), genital rash (45.5%, n=11,696), headache (29.4%, n=7,556), fatigue (29.3%, n=7,523), lymphadenopathy(all types) (29.0%, n=7,453), muscle ache (26.9%, n=6,919), general lymphadenopathy (24.3%, n=6,235), local lymphadenopathy (18.6%, n=4,779), rash of unknown location (12.7%, n=3,271), sore throat, oral rash, chills, cough, vomiting, and other signs and/or symptoms in the order of frequency, with a subtle difference between men and women. The median delay between the date of onset and reporting was 6 days (interquartile range, 3 to 9). Results that an African endemic virus has been identified more in worldwide populations than in Africa has shocked scientists which led to the question of why an African disease is becoming a global illness and why the world is currently encountering this problem.

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Section: What Are the Signs And/or Symptoms Of Human Monkeypox Virus ...mentioning

confidence: 99%

Demographic, transmission, and clinical characteristics associated with human monkeypox infection, October 2022: a systematic analysis for World Health Organization database and brief review

Yon¹

2022

Life Cycle

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“…52 People who engage in wildlife poaching, for example, are particularly vulnerable because the virus can quickly spread from an infected animal to a healthy individual. 53 The site of infection plays a very important role in the virulence of the disease. The direct contact of the body fluids of an infected person or animal with a healthy individual may lead to contamination of the serum, which may increase the lesions and rash all over the body.…”

Section: Factors Influencing the Monkeypoxmentioning

confidence: 99%

“…During pregnancy, monkeypox viruses can be transmitted from the mother to the fetus; there is a risk of miscarriage, and lesions can be seen across the placenta. 53…”

Section: Factors Influencing the Monkeypoxmentioning

confidence: 99%

Monkeypox Viruses: Resurgence of Global Threat to Mankind

Manju¹,

Ranjini²,

Raj³

et al. 2022

J. Pure Appl. Microbiol.

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The unprecedented outbreaks of monkeypox viruses in non-endemic regions have created grave concern for global health. The World Health Organization has declared a public health emergency of international concern and stated the seriousness of monkeypox viruses. The gravity of this zoonotic disease cannot be underestimated, owing to the fact that this viral infection can cause pathetic situations if ignored. Keeping these lacunas, the scientific communities have expressed their interest towards the study of monkeypox viruses. Hence the present review discusses the etiological features, historical events, and vaccination along with management strategies to combat and counter the sudden outbreak. The review also highlights the current Indian scenario of the monkeypox virus; with scanty reports available, the present contributes towards the growing scientific knowledge to prevent a future threats to mankind.

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