Mph1/MPS1 checks in at the kinetochore

Hervas-Aguilar, America; Millar, Jonathan

doi:10.1080/15384101.2016.1159888

Search citation statements

Order By: Relevance

Paper Sections

Select...

Mps1 Kinase1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2017

Publication Types

Select...

Book1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 7 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Once at kinetochores, Mps1 phosphorylates KNL1 on its repeated MELT motif allowing the recruitment of the Bub1-Bub3-BubR1 module, further strengthening the checkpoint signal (reviewed in Ref. [78]). Dynamic localization of Mps1 kinase is essential for proper kinetochore-microtubule attachment [79].…”

Section: Mps1 Kinasementioning

confidence: 99%

How are Dynamic Microtubules Stably Tethered to Human Chromosomes?

Conti¹,

Hart²,

Tamura³

et al. 2017

Cytoskeleton - Structure, Dynamics, Function and Disease

View full text Add to dashboard Cite

During cell division, microtubules capture and pull chromosomes apart into two equal sets. Without the establishment of proper chromosome-microtubule attachment, microtubules cannot impart the pulling forces needed to separate sister chromatid pairs. How are chromosomes captured along microtubule walls? How is the attachment of chromosomes to dynamic microtubule-ends achieved and monitored? We discuss these key questions by considering the roles of kinetochore-bound microtubule regulating proteins and also the complex regulatory loops of kinases and phosphatases that control chromosome-microtubule attachment and ensure the accurate segregation of chromosomes.

show abstract

Section: Mps1 Kinasementioning

confidence: 99%