Abstract:Inflammation is one contributing factors to prostate cancer (PCa). We have shown that an omega-3 (?3)-rich diet decrease PCa tumor growth by favourably modulating the inflammatory response. In this study, we tested the specific effects of purified ?3 fatty acids (FA) sub-types on tumor growth, inflammatory response, gut microbiota and tumor gene expression compared to ?6 and ?9 in a murine PCa model.METHODS: C57BL/6 mice were daily supplemented with purified FA (?3-eicosapentaenoic acid (EPA), ?3-docosahexaeno… Show more
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