Mp539dialysate Bicarbonate Variation in Patients on Regular Hemodiafiltration Program: Impact on Intradialytic Hypotension and Interdialytic Weight Gain

Abstract

Introduction and Aims: Arterial hypotension is one of the most common intradialytic complications. High ultrafiltration rates generally related to higher interdialytic weight gain are one of the major causes of this complication. Higher dialysate bicarbonate concentrations and consequent metabolic alkalosis have been associated with an increased risk of intradialytic hypotension. It has also been postulated that higher concentration of dialysate bicarbonate can be associated to greater salt and water retention and higher interdialytic weight gain. Both associations have a low level of

Temporal Changes in Electrolytes, Acid-Base, QTc Duration, and Point-of-Care Ultrasound during Inpatient Hemodialysis Sessions

“…Pre-dialysis acidosis in HD patients is associated with catabolism of protein consumed as part of a normal diet, while relative alkalosis in this population may be a marker of inadequate nutrition. [27] Alkalosis (pre-HD pH ≥7.40 compared to 7.30-7.34) was associated with higher risk of all-cause and cardiovascular mortality in 15,132 outpatients observed in Japan. [28] Especially in the setting of acute illness, poor nutrition and associated alkalosis may be a concern.…”