Mp38-14 Implementing a Multimodal Prehabilitation Program in a High-Volume Bladder Cancer Center

Jensen, Bente Thoft; Dalbagni, Guido; Jensen, Jørgen Bjerggaard; Retinger, Caitlyn; Bowker, Mallory; Love, N.

doi:10.1016/j.juro.2016.02.118

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“…A significant improvement in lean body mass (p = 0.047) and total body cells (p = 0.03) was reported at 12 months compared to the standard, accompanied by a significant reduction in the fat mass of total body weight at discharge (p = 0.04) and at day 35 (p = 0.04) and maintained a lower value throughout the follow-up period (Table 3). The same result was documented in another comprehensive cancer center with a high volume of RCs [28].…”

Section: Discussionsupporting

confidence: 78%

One-Year Follow-Up after Multimodal Prehabilitation Interventions in Radical Cystectomy

Thoft Jensen,

Bjerggaard Jensen

2023

Cancers

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Multimodal prehabilitation is the process of enhancing physiological, nutritional, and psychological resilience to increase patients’ functional capacity before major cancer surgery and aims to empower the patient to withstand the pending stress of major surgery and ultimately to improve long-term outcomes. The effect of physical prehabilitation to counteract the physical decline in surgical cancer patients has been documented; however, long-term results have not yet been published. This follow-up study aims to evaluate 1-year results on the efficacy of physical prehabilitation after bladder cancer surgery. The efficacy of prehabilitation was measured over the course of 1 year in 107 patients randomized to (1) pre- and rehabilitation or (2) standard care divided by n = 50 in the intervention (I) and n = 57 in the standard group (S). Physical function was measured by muscle leg power, and nutritional status was expressed with handgrip strength. Prehabilitation in major bladder cancer surgery can significantly improve physical function with 19.8 Watt/kg (p = 0.04), lean body mass (p = 0.047) and body cell mass (p = 0.03), and regained nutritional status one year after surgery. The results demonstrate that the restoration of physical function is vital to a full recovery.

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Section: Discussionsupporting

confidence: 78%