Mozart K.448 acts as a potential add-on therapy in children with refractory epilepsy

Lin, Lung‐Chang; Lee, Wei-Te; Wang, Chien-Hua; Chen, Hsiu-Lin; Wu, Hsien‐Tsai; Tsai, Chih-Cheng; Wei, Ruey‐Chang; Mok, Hin‐Kiu; Weng, Chia-Fen; Lee, Mei-Wen; Yang, Rei‐Cheng

doi:10.1016/j.yebeh.2010.12.044

Cited by 55 publications

(47 citation statements)

References 23 publications

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“…Lin et al [7] evaluated the efficacy of music therapy in 11 children, between 2.9 years and 14.4 years of age, with refractory cryptosymptomatic epilepsy, and treated for 6 months with music stimulation consisting of Mozart k448 every night for the duration of 8 min.…”

Section: Discussionmentioning

confidence: 99%

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Mozart's music in children with drug-refractory epileptic encephalopathies

Coppola¹,

Toro²,

Operto³

et al. 2015

Epilepsy & Behavior

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Section: Discussionmentioning

confidence: 99%

“…In fact, there are a few studies reporting that the musical stimulation, particularly the "Mozart effect" of the K448 sonata for two pianos, is able to decrease both interictal EEG discharges [1][2][3] and recurrence of clinical seizures [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Mozart's music in children with drug-refractory epileptic encephalopathies

Coppola¹,

Toro²,

Operto³

et al. 2015

Epilepsy & Behavior

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“…Particllarly, Mozart music is used to cure children with generalized seizures in clinical. Lin et al (2010Lin et al ( , 2011a reported the effect of Mozart K.448 on epileptiform discharges and seizure frequencies in Taiwanese children with generalized seizures. By continuous EEG monitoring occurred before, during, and after 8 min of exposure to the Mozart sonata, in 81 % of the patients there was a reduction in interictal discharges.…”

Section: Discussionmentioning

confidence: 99%

Exposure to Mozart music reduces cognitive impairment in pilocarpine-induced status epilepticus rats

et al. 2015

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Patients with temporal lobe epilepsy (TLE) often display cognitive deficits. However, current epilepsy therapeutic interventions mainly aim at how to reduce the frequency and degree of epileptic seizures. Recovery of cognitive impairment is not attended enough, resulting in the lack of effective approaches in this respect. In the pilocarpine-induced temporal lobe epilepsy rat model, memory impairment has been classically reported. Here we evaluated spatial cognition changes at different epileptogenesis stages in rats of this model and explored the effects of long-term Mozart music exposure on the recovery of cognitive ability. Our results showed that pilocarpine rats suffered persisting cognitive impairment during epileptogenesis. Interestingly, we found that Mozart music exposure can significantly enhance cognitive ability in epileptic rats, and music intervention may be more effective for improving cognitive function during the early stages after Status epilepticus. These findings strongly suggest that Mozart music may help to promote the recovery of cognitive damage due to seizure activities, which provides a novel intervention strategy to diminish cognitive deficits in TLE patients.

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“…Interestingly, relaxation without music does not reduce the number of epileptic discharges [70]. Mozart's music has antiepileptic effects in children as well [71].…”

Section: Archivos De Medicina Issn 1698-9465 Journal Of Neurology Andmentioning

confidence: 98%

Neurologic Music Therapy to Facilitate Recovery from Complications of Neurologic Diseases

Bahrami¹,

Thomas²,

Bahrami³

et al. 2017

J Neurol Neurosci

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Neurologic music therapy (NMT) has fostered recovery from complications in patients suffering from a wide variety of neurologic diseases. Combining music and virtual reality with standard rehabilitation therapies can improve patient compliance and make therapy more enjoyable. Listening to music can reduce epileptiform discharges and enhances brain plasticity. Music produces variations in brain anatomy between musicians and non-musicians. Music therapy is an inexpensive intervention to help post-stroke patients to recover faster and more efficiently if applied soon after the event. There is evidence that incorporating music into a rehabilitation program fosters recovery of hand function, dexterity, spatial movement, cognitive function, mood, coordination, stride length and memory. Learning words as lyrics, melodic intonation therapy and singing can help the aphasic patient to recover faster. NMT therapists are valuable members of the rehabilitation team. NMT has been approved by the World Rehabilitation Federation as an effective evidence based method of treatment.

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Mozart K.448 acts as a potential add-on therapy in children with refractory epilepsy

Cited by 55 publications

References 23 publications

Mozart's music in children with drug-refractory epileptic encephalopathies

Mozart's music in children with drug-refractory epileptic encephalopathies

Exposure to Mozart music reduces cognitive impairment in pilocarpine-induced status epilepticus rats

Neurologic Music Therapy to Facilitate Recovery from Complications of Neurologic Diseases

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