Moving to Maintain Function in Knee Osteoarthritis: Evidence From the Osteoarthritis Initiative

Dunlop, Dorothy D.; Semanik, Pamela A.; Song, Jing; Sharma, Leena; Nevitt, M.; Jackson, Rebecca D.; Mysiw, Jerry; Chang, Rowland W.

doi:10.1016/j.apmr.2010.01.015

Cited by 49 publications

(37 citation statements)

References 39 publications

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“…A large body of literature exists on the beneficial relationships between physical activity and health outcomes including reduced risk of cardiovascular disease and early mortality as well as maintenance of functional status (41–44). Beneficial effects of physical activity on health outcomes have been described in the general adult population as well as in patients with or at risk for osteoarthritis (41, 45).…”

Section: Discussionmentioning

confidence: 99%

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Relationship of Meeting Physical Activity Guidelines With Health‐Related Utility

Sun

Song

Lee

et al. 2014

Arthritis Care & Research

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Objective Health-related utility measures overall health status and quality of life and is commonly incorporated into cost-effectiveness analyses. This study investigates whether attainment of federal physical activity guidelines translates into better health-related utility in adults with or at risk for knee osteoarthritis (OA). Methods Cross-sectional data from 1908 adults with or at risk for knee OA participating in the accelerometer ancillary study of the Osteoarthritis Initiative (OAI) were assessed. Physical activity was measured using 7 days of accelerometer monitoring and was classified as 1) Meeting Guidelines (≥150 bouted moderate-to-vigorous [MV] minutes per week); 2) Insufficiently Active (≥1 MV bout[s] per week but below guidelines); or 3) Inactive (zero MV bouts per week). A Short Form 6D (SF6-D) health-related utility score was derived from patient-reported health status. Relationship of physical activity levels to median health-related utility adjusted for socioeconomic and health factors was tested using quantile regression. Results Only 13% of participants met physical activity guidelines; 45% were inactive. Relative to the Inactive, median health-related utility scores were significantly greater for the Meeting Guidelines (0.063; confidence interval [CI] 0.055–0.071) and Insufficiently Active (0.059; CI 0.054–0.064) groups. These differences showed a statistically significant linear trend and strong cross-sectional relationship with physical activity level even after adjusting for socioeconomic and health factors. Conclusions We found a significant positive relationship between physical activity level and health-related utility. Interventions that encourage adults, including persons with knee OA, to increase physical activity even if recommended levels are not attained may improve their quality of life.

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Section: Discussionmentioning

confidence: 99%

“…Beneficial effects of physical activity on health outcomes have been described in the general adult population as well as in patients with or at risk for osteoarthritis (41, 45). However, few studies specifically examined physical activity in relation to cost-effectiveness or quality of life outcomes.…”

Section: Discussionmentioning

confidence: 99%

Relationship of Meeting Physical Activity Guidelines With Health‐Related Utility

Sun

Song

Lee

et al. 2014

Arthritis Care & Research

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“…However, few such studies have been undertaken in Western countries [12][13][14][15], and none have been reported in Japan. We evaluated performance-based measures of physical functioning (chair stand time, walking time, and functional reach) in community-dwelling Japanese women to clarify associations with radiographic or painful knee OA.…”

Section: Introductionmentioning

confidence: 99%

Physical performance and knee osteoarthritis among community-dwelling women in Japan: the Hizen-Oshima Study, cross-sectional study

et al. 2011

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Osteoarthritis (OA) is the most common chronic joint disorder. Relationships between knee OA and physical performance have been examined, but mainly in patients with knee OA. Clarifying the relationship between knee OA and physical performance among community-dwelling individuals is thus important. Subjects comprised 563 community-dwelling Japanese women. Radiographic knee OA was defined as Kellgren-Lawrence criteria grade 2 or higher. Painful knee OA was defined as radiographic OA combined with knee pain. We evaluated performance-based measures of physical functioning. Student's t tests were used to compare continuous variables. Adjusted means of performance-based measures were compared between groups using general linear modeling methods. Mean age was 64.3 years. Women with radiographic OA were older than those without OA (P < 0.0001). BMI was greater in women with radiographic OA than in women without OA (P < 0.0001). In univariate analysis, women with radiographic OA displayed worse physical functioning than women without OA, with longer chair stand time, longer walking time, and shorter functional reach. Performance-based measurements with painful OA resembled those with radiographic OA. Age- and BMI-adjusted means of chair stand time and walking time were longer in women with radiographic or painful knee OA than in women without OA (P < 0.0001 each). Furthermore, chair stand and walking took longer for women with painful knee OA than for women with radiographic knee OA. Women with knee OA showed deteriorated performance of chair stand and walking. Painful knee OA was associated with poorer performance than radiographic knee OA.

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“…Although, results of these studies have demonstrated that exercises are usually effective only for a short term, exercises are still the mainstay of conservative treatment [7]. For knee osteoarthritis, regular physical activity is known to have beneficial effects on the quality of life [8, 9] and physical functions of the affected patients [10, 11]. However, the level of activity in relation to depression and particularly sleep quality has not been investigated adequately.…”

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confidence: 99%

Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis

Mesci¹

2016

North Clin Istanbul

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OBJECTIVE:In the present study, we aimed to investigate the effects of physical activity level on the quality of life, depression, sleep quality and functional capacity in elderly patients with knee osteoarthritis (OA).METHODS:Fifty-five patients over 65 years of age (age range: 65–84 years) with knee osteoarthritis were enrolled in the study. Patients were divided into two groups including Insufficient Activity Group (IAG) and Physically Active Group (PAG) according to their responses to the International Physical Activity Questionnaire. Radiological OA grading was performed using Kellgren-Lawrence classification system. Patients were evaluated using Short-Form 36 (SF-36) questionnaire, Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).RESULTS:Mean age, body mass indices, mean pain scores and gender distribution were comparable between the two groups. WOMAC physical function scores were lower in the Physically Active Group (p=0.01). Mean PSQI scores did not differ statistically significantly between the two groups (p=0.242). Mean BDI score of PAG was significantly lower compared to that of IAG (p=0.015). Mean SF-36 physical function (p=0.044), physical role (p=0.008) and physical component (p=0.016) scores of the Physically Active Group were significantly higher vs Insufficient Activity Group.CONCLUSION:Maintaining a high physical activity level reduces the possibility of depression and improves the quality of life and functional capacity in geriatric patients with knee osteoarthritis.

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Moving to Maintain Function in Knee Osteoarthritis: Evidence From the Osteoarthritis Initiative

Cited by 49 publications

References 39 publications

Relationship of Meeting Physical Activity Guidelines With Health‐Related Utility

Relationship of Meeting Physical Activity Guidelines With Health‐Related Utility

Physical performance and knee osteoarthritis among community-dwelling women in Japan: the Hizen-Oshima Study, cross-sectional study

Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis

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