Moving from conventional to adaptive risk stratification for oropharyngeal cancer
Vlad C. Sandulache,
R. Parker Kirby,
Stephen Y. Lai
Abstract:Oropharyngeal cancer (OPC) poses a complex therapeutic dilemma for patients and oncologists alike, made worse by the epidemic increase in new cases associated with the oncogenic human papillomavirus (HPV). In a counterintuitive manner, the very thing which gives patients hope, the high response rate of HPV-associated OPC to conventional chemo-radiation strategies, has become one of the biggest challenges for the field as a whole. It has now become clear that for ~30-40% of patients, treatment intensity could b… Show more
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