Mouth cavity base defect treated with biosynthetic graft

Vojtassák, J; Poruban, D.; Bakoš, Dušan; Danihel, Ľ; Korbeľ, M; Danišovič, Ľuboš; Böhmer, Daniel; Danihelová, Angelika; Michalka, Peter; Vojtaššák, Branislav; Blaŝko, M

doi:10.2478/s11756-006-0146-1

Cited by 6 publications

(5 citation statements)

References 9 publications

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“…There have been several studies reporting the intravenous or intradermal application of MSCs to improve the cutaneous wound healing of acute incisional and excisional wounds, diabetic ulcers, radiation ulcers, and acute or chronic skin injuries in humans and animals, including burn injuries 23,[28][29][30] . In the present study, the application of adipose-derived MSCs was found to diminish the burn site in burn wounds in rats, and provided a significantly higher degree of healing (p<0.05).…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Effects of Stem Cell, Platelet Rich Plasma and Ovarian Follicle Fluid on Burn Stasis Zone (Experimental Study)

Genç¹,

Soylu²,

İnan³

et al. 2021

Cumhuriyet Medical Journal

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The basic aim in the treatment of second-degree burns is to prevent progressive cell death, and so treatments are directed at the zone of stasis. In this study, We were aimed to investigate the healing effects of using Mesenchymal Stem Cells (MSCs), Ovarian follicular fluid (OFS) and Platelet-rich plasma (PRP) on burn stasis zone in an experimental burn model. Method: Forty rats were divided randomly into four groups. Burns were created in each group according to the comb burn model. The control group received no treatment; the mesenchymal stem cell [MSC] group received MSC; the platelet-rich plasma [PRP] group received PRP; and the ovarian follicular fluid [OFF] group received OFF subcutaneously on days 1, 3 and 5. On days 1 and 21, all rats were photographed and the burn sites were calculated. At the end of day 21, all rats were sacrificed, the dorsum containing the created burns were excised, and the epithelialization, collagen amount, fibroblast density, inflammatory cell density and VEGF amounts were evaluated histopathologically. Results: The groups were assessed based on the burn site healing rate and histopathological scoring. Healing was faster in the MSC group [p<0.005], PRP group [p>0.005] and OFS group [p<0.005] than in the control group. When the treatment groups were compared with each other, the best healing was observed in the MSC, PRP and OFF groups, respectively. Conclusions: MSC, PRP and OFF were found to have a positive effect on burn healing, with MSC being the most efficient method among the three, followed by PRP and OFF, respectively, which were found to provide a faster healing than the control group.

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Section: Discussionmentioning

confidence: 99%

Comparison of the Effects of Stem Cell, Platelet Rich Plasma and Ovarian Follicle Fluid on Burn Stasis Zone (Experimental Study)

Genç¹,

Soylu²,

İnan³

et al. 2021

Cumhuriyet Medical Journal

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“…We evaluated foot posture from the rear as we focused on the ankle joint: a) (1 point)slim ankles touching each other, good upright posture, b) (2 points) -ankles are slightly turned inwards, c) (3 points) -ankles roll excessively inwards, overpronated feet collapse inwards, bad posture. Pain intensity was measured by means of the visual analogue scale (VAS) -an 11-point Likert scale: 0 = no pain, 10 = pain as bad as it could possibly be (Vojtaššák, 2000).…”

Section: Methodsmentioning

confidence: 99%

Selected Factors Influencing the Qualitative Level of Postural Health of Students in Slovakia

2023

European Journal of Contemporary Education

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The current modern lifestyle of the 21st century has acquired a hypokinetic and sedentary character among the school population, which was further strongly supported by the global Covid-19 pandemic. This further supported the space for the upward trend of diseases, which also include disorders in the musculoskeletal system, postural health. The aim of our study was to find out and point out the factors, which determine the quality of postural health in adolescent students, and their mutual relationships. The sample consisted of 518 students in Slovakia, 266 girls aged(x) 16.5 ± 2.1 years (body height(x) 169.6 ± 6.8 cm, body weight(x) 60.2 ± 7.2 kg) and 252 boys aged(x) 16.9 ± 1.9 years (body height(x) 177.3 ± 8.5 cm, body weight(x) 66.4 ± 7.1 kg). In terms of data acquisition methods in the observed, standardized methods of physical education and pedagogical practice were used. The findings show that in the overall physical regime of students there are significant differences between the genders to the detriment of girls (p < 0.05) in terms of volume of physical activities, frequency and intensity (p < 0.05). The sedentary lifestyle in both genders showed a lack of physical activity in association with poor posture (r = 0.789) (sagittal and frontal plane). Also, higher food intake than energy expenditure results in higher body weight in the sample, which was reflected in the lower limbs (LL to X, r = 0.717 and foot pain r = 0.739 and fallen arch r = 0.726). In the observed sample, incorrect wearing of school bags was also found, significantly (p < 0.05) to the detriment of girls, as well as wearing incorrect shoes for both genders. These findings suggest that there are risk factors in students' lifestyles that contribute to the quality of their postural health, which need to be given much more attention in terms of primary prevention in both school and out-of-school environments. This project was supported by VEGA 1/0427/22 "Prevention of students' postural health by physical activity".

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“…Following 29 days of the treatment, there was a steady overall reduction in the wound size, yet an increase in the dermal vascularity and thickness at the wound area. [232] One potential drawback in MSC therapy is their low viability after implantation, which lessens their safety profile over a long period. Nevertheless, several strategies have been suggested to enhance the survival of MSCs after transplantation.…”

Section: Mesenchymal Stem/stromal Cells (Mscs)mentioning

confidence: 99%

Engineering Bioactive Scaffolds for Skin Regeneration

Hosseini

Shafiee

2021

Small

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The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/smll.202101384.The mechanical properties of the skin are important for understanding the pathophysiology of skin diseases and engineering Large skin wounds pose a major clinical challenge. Scarcity of donor site and postsurgical scarring contribute to the incomplete or partial loss of function and aesthetic concerns in skin wound patients. Currently, a wide variety of skin grafts are being applied in clinical settings. Scaffolds are used to overcome the issues related to the misaligned architecture of the repaired skin tissues. The current review summarizes the contribution of biomaterials to wound healing and skin regeneration and addresses the existing limitations in skin grafting. Then, the clinically approved biologic and synthetic skin substitutes are extensively reviewed. Next, the techniques for modification of skin grafts aiming for enhanced tissue regeneration are outlined, and a summary of different growth factor delivery systems using biomaterials is presented. Considering the significant progress in biomaterial science and manufacturing technologies, the idea of biomaterial-based skin grafts with the ability for scarless wound healing and reconstructing full skin organ is more achievable than ever.

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Mouth cavity base defect treated with biosynthetic graft

Cited by 6 publications

References 9 publications

Comparison of the Effects of Stem Cell, Platelet Rich Plasma and Ovarian Follicle Fluid on Burn Stasis Zone (Experimental Study)

Comparison of the Effects of Stem Cell, Platelet Rich Plasma and Ovarian Follicle Fluid on Burn Stasis Zone (Experimental Study)

Selected Factors Influencing the Qualitative Level of Postural Health of Students in Slovakia

Engineering Bioactive Scaffolds for Skin Regeneration

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