Mouse monoclonal antibodies to swine blood group antigens

Abstract

Summary. Eight mouse hybridomas with haemagglutination capacity to swine blood group antigens were obtained, three of them producing antibodies capable of being used as blood group reagents. Two detected the Ba factor and another the Fa factor. The others gave non‐specific and weak reactions or cross‐reaction with antigens present in more than one system. We conclude that mouse monoclonal antibodies are also suitable for use in swine as a complement of polyclonal reagents.

A monoclonal antibody to swine erythrocytes recognizes the B blood group on the major glycophorin

“…These results confirm that ZGz reacts more strongly with cells with the B" allele of the B system of the swine blood group (Gonzalez et al 1992). 2G2 presents a similar behaviour to that of 1AC11, which recognizes the major glycoprotein in swine but not in other species.…”