Mouse Lumbar Vertebra Uniaxial Compression Testing with Embedding of the Loading Surface
Chandler A. Sparks,
Ryeim B. Ansaf,
Annette M. Gabaldón
Abstract:There is increasing awareness that cortical and cancellous bone differ in regulating and responding to pharmaceutical therapies, hormone therapies, and other treatments for age-related bone loss. Three-point bending is a common method used to assess the influence of a treatment on the mid-diaphysis region of long bones, which is rich in cortical bone. Uniaxial compression testing of mouse vertebrae, though capable of assessing bones rich in cancellous bone, is less commonly performed due to technical challenge… Show more
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