Mouse Genetic Nomenclature

Sundberg, John P.; Begley, Dale A.; Berry, Michael; Perry, Michelle N.; Shaw, David; Schofield, Paul N.

doi:10.1002/9781119624608.ch3

Cited by 1 publication

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“…There are many other specific genetic tools (such as consomic strains, where one chromosome has been replaced with that of another strain) available as described in detail elsewhere. 78…”

Section: Nomenclaturementioning

confidence: 99%

“…There are many other specific genetic tools (such as consomic strains, where one chromosome has been replaced with that of another strain) available as described in detail elsewhere. 78 As a specific example of how to use nomenclature, creating white (albino) mice from pigmented mice can illustrate its importance. Pigment, regardless of type, can interfere with interpretation of phenotypes or specific assays, such as immunohistochemistry using dark-brown chromogens (diaminobenzidine) or looking for fine details with hair shafts.…”

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confidence: 99%

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Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex

Sundberg

Rice

2023

Vet Pathol

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The skin and adnexa can be difficult to interpret because they change dramatically with the hair cycle throughout life. However, a variety of methods are commonly available to collect skin and perform assays that can be useful for figuring out morphological and molecular changes. This overview provides information on basic approaches to evaluate skin and its molecular phenotype, with references for more detail, and interpretation of results on the skin and adnexa in the mouse. These approaches range from mouse genetic nomenclature, setting up a cutaneous phenotyping study, skin grafts, hair follicle reconstitution, wax stripping, electron microscopy, and Köbner reaction to very specific approaches such as lipid and protein analyses on a large scale.

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“…There are many other specific genetic tools (such as consomic strains, where one chromosome has been replaced with that of another strain) available as described in detail elsewhere. 78…”

Section: Nomenclaturementioning

confidence: 99%

mentioning

confidence: 99%