Mounier-Kuhn syndrome: an unusual underlying cause for chronic coughs and recurrent pneumonias

Ip, Janice; Hui, Peter; Lam, Selay; Lam, Wendy; Chau, MW

doi:10.12809/hkmj133760

Cited by 4 publications

(2 citation statements)

References 4 publications

(4 reference statements)

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“…Our patient's age at diagnosis was similar to that reported by other authors, as most cases are diagnosed at ages 40-50 years [12,13]. Although most reported cases have chronic cough and the vast majority are asymptomatic, there are cases, like our patient, in which lung capacity is severely impaired [12,13].…”

Section: Discussionsupporting

confidence: 84%

Recurrent Pneumonias in a Previously Healthy and Immunocompetent Young Adult: A Case Report Mounier-Kuhn Syndrome

et al. 2020

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syndrome is a rare clinical condition characterized by marked tracheal and bronchial dilatation. It is commonly associated with multiple respiratory infections due to the inability to mobilize secretions, chronic cough, and decline in lung capacity. Although it is a rare disease, the number of cases reported in the literature has increased, and physicians should be aware of its existence to be able to recognize and diagnose it. Suspicion should arise regarding young adults who develop recurrent airway infections when immunosuppression has been ruled out. Case Report: We present the case of a young adult, previously healthy and immunocompetent, who was diagnosed with Mounier-Kuhn syndrome after 5 years of multiple respiratory infections and multiple respiratory failures, who received intensive care management with multiple complications and difficulties in achieving adequate ventilation. Due to the risk of respiratory failure and major complications, its management was challenging. We were able to treat this patient and prevent complications with a multidisciplinary approach with a strong emphasis on constant and intense pulmonary therapy. Conclusions: Mounier-Kuhn syndrome is rare but does occur, and physicians need to have a high index of suspicion to diagnose it. Its management must be done by a multidisciplinary team, and respiratory therapy should be constantly available at bedside.

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Section: Discussionsupporting

confidence: 84%

Recurrent Pneumonias in a Previously Healthy and Immunocompetent Young Adult: A Case Report Mounier-Kuhn Syndrome

et al. 2020

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“…[2][3][4][5] Two cases were previously reported. 6,7 The medical histories were entered into GPT-4 on the same day with exact script copied out and further analyzed (Supplementary file 1 in Data S1). We extracted the primary diagnosis, differential diagnoses and work-up as suggested by GPT-4 and compared these with those documented by the clinician.…”

mentioning

confidence: 99%

Limitations of GPT‐4 in analyzing real‐life medical notes related to cognitive impairment

Shea

2023

Psychogeriatrics

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Mounier-Kuhn Syndrome in an Elderly Female with Pulmonary Fibrosis

Boglou

Παπάνας

Oikonomou

et al. 2016

Case Reports in Medicine

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Mounier-Kuhn syndrome (MKS), or tracheobronchomegaly, is a rare clinical and radiologic condition characterized by pronounced tracheobronchial dilation and recurrent lower respiratory tract infections. Tracheobronchomegaly presents when the defect extends to the central bronchi. MKS can be diagnosed in adult women when the transverse and sagittal diameters of the trachea, right mainstem bronchus, and left mainstem bronchus exceed 21, 23, 19.8, and 17.4 mm, respectively. Its diagnosis is based on chest radiograph and chest computed tomography (CT). Patients, usually middle-aged men, may be asymptomatic or present with clinical manifestations ranging from minimal symptoms with preserved lung function to severe respiratory failure. Pulmonary function tests (PFTs) typically reveal a restrictive pattern. This report presents an elderly woman with previously diagnosed pulmonary fibrosis with symptoms of increased sputum production and haemoptysis. High-resolution chest CT showed tracheal and main stem bronchi dilatation along with bronchial diverticulosis. PFTs indicated a restrictive pattern characteristic of the underlying pulmonary fibrosis. The patient is the oldest, referred to the female gender, at presentation of MKS hitherto reported. This case highlights the need to include MKS in the differential diagnosis of recurrent lower respiratory tract infections, even in older subjects.

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Mounier-Kuhn syndrome: an unusual underlying cause for chronic coughs and recurrent pneumonias

Cited by 4 publications

References 4 publications

Recurrent Pneumonias in a Previously Healthy and Immunocompetent Young Adult: A Case Report Mounier-Kuhn Syndrome

Recurrent Pneumonias in a Previously Healthy and Immunocompetent Young Adult: A Case Report Mounier-Kuhn Syndrome

Limitations of GPT‐4 in analyzing real‐life medical notes related to cognitive impairment

Mounier-Kuhn Syndrome in an Elderly Female with Pulmonary Fibrosis

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