Mounier-Kuhn Syndrome: A Rare Cause of a Common Disease

Mesiha, Nabil; Mogla, Ankur; Alipour, Mona; Chiu, Jennifer L.; Vasudevan, Viswanath; Arjomand, Farhad; Gerolemou, Louis

doi:10.1016/j.chest.2018.08.526

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2020

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“…7,9À12 The clinical presentations of MKS are not specific and include a wide spectrum of clinical features ranging from asymptomatic or minimal disease to progressive manifestations leading to respiratory failure. 13 Common presentations are chronic productive cough, dyspnea and recurrent respiratory infections due to of mucociliary dysfunction and accumulation of secretions. 11,14,15 MKS' diagnosis relies on detection of enlarged diameter of the trachea, right and left main bronchi by CT scan.…”

Section: Discussionmentioning

confidence: 99%

Early manifestation of ARDS in COVID-19 infection in a 51- year-old man affected by Mounier-Kuhn syndrome

et al. 2020

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A 51-year-old man known to be affected by Mounier-Kuhn syndrome (MKS). presented to Accident & Emergecy (A&E) with fever, dyspnea and deterioration of his chronic coughs. Increased diameters of his trachea (39 mm), right (30 mm) and left (26 mm) main bronchi were revealed by chest computerized tomography (CT) scan. CT scan showed also ground-glass opacities (GGO) and bronchiectasis in the mid and lower zones of both lungs. COIVD-19 infection was eventually confirmed by RT-PCR. A severe form of COVID-19 could occur even in the early stages of the disease in presence of underlying co-morbidities including MKS, which increases the susceptibility to more recurrent and severe respiratory infections.

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Section: Discussionmentioning

confidence: 99%