Motorized head impulse rotator in patients with vestibular schwannoma

Hirvonen, Meeli; Aalto, Heikki; Hirvonen, Timo

doi:10.1080/00016480801908027

Cited by 10 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results suggest that the resulting sensation of balance would be less affected during daily activities, since they are largely comprised of active movements. Indeed, this proposal is consistent with the reported lack of correlation between the subjective sensation of dizziness (i.e., presumably derived in part from the modulation of VO neurons) and the VOR gain asymmetry measured by caloric test and passive head impulse test (i.e., mediated by PVP neurons that continue to help stabilize gaze during active head motion) in patients with unilateral vestibular loss (Hirvonen et al 2008).…”

Section: Cancellation Of Vestibular Signals During Active Head Rotationssupporting

confidence: 75%

Multimodal Integration After Unilateral Labyrinthine Lesion: Single Vestibular Nuclei Neuron Responses and Implications for Postural Compensation

Sadeghi

Minor

Cullen

2011

Journal of Neurophysiology

View full text Add to dashboard Cite

Sadeghi SG, Minor LB, Cullen KE. Multimodal integration after unilateral labyrinthine lesion: single vestibular nuclei neuron responses and implications for postural compensation. J Neurophysiol 105: 661-673, 2011. First published December 8, 2010 doi:10.1152/jn.00788.2010. Plasticity in neuronal responses is necessary for compensation following brain lesions and adaptation to new conditions and motor learning. In a previous study, we showed that compensatory changes in the vestibuloocular reflex (VOR) following unilateral vestibular loss were characterized by dynamic reweighting of inputs from vestibular and extravestibular modalities at the level of single neurons that constitute the first central stage of VOR signal processing. Here, we studied another class of neurons, i.e., the vestibular-only neurons, in the vestibular nuclei that mediate vestibulospinal reflexes and provide information for higher brain areas. We investigated changes in the relative contribution of vestibular, neck proprioceptive, and efference copy signals in the response of these neurons during compensation after contralateral vestibular loss in Macaca mulata monkeys. We show that the time course of recovery of vestibular sensitivity of neurons corresponds with that of lower extremity muscle and tendon reflexes reported in previous studies. More important, we found that information from neck proprioceptors, which did not influence neuronal responses before the lesion, were unmasked after lesion. Such inputs influenced the early stages of the compensation process evidenced by faster and more substantial recovery of the resting discharge in proprioceptive-sensitive neurons. Interestingly, unlike our previous study of VOR interneurons, the improvement in the sensitivity of the two groups of neurons did not show any difference in the early or late stages after lesion. Finally, neuronal responses during active head movements were not different before and after lesion and were attenuated relative to passive movements over the course of recovery, similar to that observed in control conditions. Comparison of compensatory changes observed in the vestibuloocular and vestibulospinal pathways provides evidence for similarities and differences between the two classes of neurons that mediate these pathways at the functional and cellular levels.

show abstract

Section: Cancellation Of Vestibular Signals During Active Head Rotationssupporting

confidence: 75%

Multimodal Integration After Unilateral Labyrinthine Lesion: Single Vestibular Nuclei Neuron Responses and Implications for Postural Compensation

Sadeghi

Minor

Cullen

2011

Journal of Neurophysiology

View full text Add to dashboard Cite

show abstract

“…Earlier experiments with healthy subjects and patients have not shown any significant decoupling of the helmet and head with the used stimulus profile [10,11]. Eye position was monitored with conventional electro-oculography: two active electrodes were attached to the lateral canthi of the eyes and the ground electrode was mounted to the forehead without coupling to the helmet.…”

Section: Protocolmentioning

confidence: 99%

“…The motorized head impulse test (MHIT) providing horizontal head rotations resembling those encountered during natural locomotion, was introduced recently in normal subjects and in patients with vestibular schwannoma [10,11]. In the present study we followed patients with acute unilateral peripheral vestibular loss sequentially with the MHIT.…”

Section: Introductionmentioning

confidence: 98%

Recovery of the horizontal vestibulo-ocular reflex in motorized head impulse test is common after vestibular loss

Jutila¹,

Aalto²,

Hirvonen³

2012

Acta Oto-Laryngologica

Self Cite

View full text Add to dashboard Cite

show abstract

“…The motorized head impulse test (MHIT) has been introduced in healthy subjects (17) and patients with vestibular schwannoma (18) and vestibular neuritis (19). In the present prospective study, we followed vestibular function in patients with cochlear implants preoperatively and postoperatively with the MHIT.…”

mentioning

confidence: 99%

Cochlear Implantation Rarely Alters Horizontal Vestibulo-ocular Reflex in Motorized Head Impulse Test

Jutila

Aalto

Hirvonen

2013

Otology &Amp; Neurotology

Self Cite

View full text Add to dashboard Cite

show abstract

Motorized head impulse rotator in patients with vestibular schwannoma

Cited by 10 publications

References 17 publications

Multimodal Integration After Unilateral Labyrinthine Lesion: Single Vestibular Nuclei Neuron Responses and Implications for Postural Compensation

Multimodal Integration After Unilateral Labyrinthine Lesion: Single Vestibular Nuclei Neuron Responses and Implications for Postural Compensation

Recovery of the horizontal vestibulo-ocular reflex in motorized head impulse test is common after vestibular loss

Cochlear Implantation Rarely Alters Horizontal Vestibulo-ocular Reflex in Motorized Head Impulse Test

Contact Info

Product

Resources

About