“…There are also scholars, such as Rühm et al, who used molecular stereotactic biopsy to accurately locate gliomas [19]. However, the current comprehensive treatment has certain side effects, such as incomplete removal by surgery, destruction of functional areas, and indiscriminate killing of normal nerve cells and glioma cells by radioactive elements during radiation therapy [20,21]. Chemotherapy, in contrast, is not only limited by the drug tolerance of glioma (e.g., platinum-based chemotherapeutic agents, a class of chemotherapeutic agents that affect the cell cycle, are not effective, because gliomas are resistant to platinum-based drugs [22]) but also decreases neurocognitive and other functions [23,24].…”