Motor neuron disease in textile factory workers

Abarbanel, J. M.; Herishanu, Y.; Osimani, Alicia; Frisher, S

doi:10.1111/j.1600-0404.1989.tb03796.x

Cited by 11 publications

(7 citation statements)

References 6 publications

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“…Moreover, the results of previous case-control studies are hardly comparable because the classifica tion of professions is often different. Pre vious reports have suggested the association of MND with various occupations, including job exposure to heavy metals [22,26,27] and to solvents and glues [29,30]; farming [23]; professional contact with animal hides and carcasses [10]; leather [31] and textile workers [43]; occupations at risk of electrical exposure [11,12], and heavy manual labor ers [23,32]. Other studies gave negative results (table 7).…”

Section: Discussionmentioning

confidence: 99%

Risk Factors in Motor Neuron Disease: A Case-Control Study

et al. 1991

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A case-control study of risk factors in 512 cases of motor neuron disease (MND) and 512 controls, affected by other neurological diseases, was performed. Clinical history showed a significant increase in gastric ulcer and mechanical injuries among MND cases, whereas the frequencies of operations, poliomyelitis, malignancies and autoimmune diseases were similar for cases and controls. The women affected by MND had a later menarche and an earlier menopause; therefore, the reproductive period was significantly shorter, supporting a possible role of sexual hormones in the pathogenesis of MND. The analysis of occupations showed an increased number of farmers and also of subjects exposed to chemical products among MND cases.

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Section: Discussionmentioning

confidence: 99%

Risk Factors in Motor Neuron Disease: A Case-Control Study

et al. 1991

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“…Previous epidemiological investigations have suggested an association between ALS and some environmental risk factors [8][9][10][11]. Mechanical injuries and skeletal fractures have been considered to play an important role in the etiology of ALS [9,12,13].…”

Section: Discussionmentioning

confidence: 99%

A Case-Control Study of Amyotrophic Lateral Sclerosis

et al. 1991

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A retrospective case-control study was conducted using 46 patients affected by amyotrophic lateral sclerosis and 92 closely matched healthy controls. Cases were ascertained through typical clinical and instrumental findings. Putative risk factors (bone fractures or major trauma, exposure to domestic animals, surgical operations, disease among first degree relatives and others) were investigated anamnestically using a standard questionnaire. Using Mantel-Haenzsel estimates of the odds ratio, no association was found between amyotrophic lateral sclerosis and the investigated variables.

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“…Environmental factors are being exten sively investigated [1], There are reports of increased incidence of ALS in textile factory workers [2] and leather workers [3] while several studies report increased ALS inci dence among farmers [4][5][6][7][8] or among people who perform heavy manual labor [4,9,10]. The subject remains controversial, however, since there are studies that report no in creased incidence of ALS among leather workers [11], farmers [12][13][14] or those who perform manual labor [14], This study investigates the possible role of environmental factors in the etiology of ALS by screening the population of ALS patients in our hospital over the last 25 years.…”

Section: Introductionmentioning

confidence: 99%

Amyotrophic Lateral Sclerosis in Southern Greece: An Epidemiologic Study

et al. 1991

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All amyotrophic lateral sclerosis cases hospitalized over a 25-year period in the University Department of Neurology in Athens were surveyed, with emphasis given to the occupation of the patients and the geographic distribution of the disease. The results showed an overrepresentation of farmers among patients and an aggregation of cases in the region of Cephalonia. These findings might suggest that environmental factors could be involved in the etiology of the disease.

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Motor neuron disease in textile factory workers

Cited by 11 publications

References 6 publications

Risk Factors in Motor Neuron Disease: A Case-Control Study

Risk Factors in Motor Neuron Disease: A Case-Control Study

A Case-Control Study of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis in Southern Greece: An Epidemiologic Study

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