1990
DOI: 10.1007/978-1-4613-1495-0_18
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Motor Neuron Disease

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Cited by 9 publications
(4 citation statements)
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“…Neurodegeneration starts locally and spreads from one myotome segment to the segment next to it (53)(54)(55). This domino-like propagation of the pathology has previously been taken as evidence for a viral infection accompanying the disease (56).…”
Section: Discussionmentioning
confidence: 99%
“…Neurodegeneration starts locally and spreads from one myotome segment to the segment next to it (53)(54)(55). This domino-like propagation of the pathology has previously been taken as evidence for a viral infection accompanying the disease (56).…”
Section: Discussionmentioning
confidence: 99%
“…18 The difference in innervation between the SCM and the tongue may explain the different EMG sensitivities for these two muscles. With rostral progression of LMN degeneration, the upper cervical cord will be involved before the medulla, 3 and needle EMG abnormalities will occur in the SCM before the tongue. This would explain why in limb-onset ALS patients with no bulbar symptoms, EMG studies of the SCM were more often abnormal than examination of the tongue.…”
Section: Discussionmentioning
confidence: 99%
“…The average age of speakers in the female group was 58.2 years (SD = 11.2, range = 48 -86). The age range of participants corresponded with that of a typical population affected by ALS (Brooks et al, 1991). All but 4 participants (N012, N016, N020, N023) grew up in English speaking Canada or the United States.…”
Section: Methods Participantsmentioning
confidence: 99%