Motor learning changes the axon initial segment of the spinal motoneuron
Yu Wang,
Yi Chen,
Lu Chen
et al.
Abstract:We are studying the mechanisms of H‐reflex operant conditioning, a simple form of learning. Modelling studies in the literature and our previous data suggested that changes in the axon initial segment (AIS) might contribute. To explore this, we used blinded quantitative histological and immunohistochemical methods to study in adult rats the impact of H‐reflex conditioning on the AIS of the spinal motoneuron that produces the reflex. Successful, but not unsuccessful, H‐reflex up‐conditioning was associated with… Show more
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