Motor Functions of the Superior Colliculus

Gandhi, Neeraj J.; Katnani, Husam A.

doi:10.1146/annurev-neuro-061010-113728

Cited by 422 publications

(377 citation statements)

References 174 publications

Supporting

Mentioning

342

Contrasting

Unclassified

Order By: Relevance

“…An alternative hypothesis emerges from the literature on spatial attention, particularly that on visual attention in primates including humans (Gandhi and Katnani, 2011). This approach suggests that actions, such as eye movements and reaches towards targets, are generated by first computing a Ôsalience mapÕ that integrates information about the relevance (salience) to the animal of particular locations in space into a single topographic representation.…”

Section: A Control Architecture For Behavioural Integration In Vibrismentioning

confidence: 99%

“…In primates, foveation is well studied with respect to the visual system and is known to be mediated by the Superior Colliculus (SC) (Gandhi and Katnani, 2011). In rats, stimulation of SC can evoke not only eye movements (McHaffie and Stein, 1982), but also orienting-like movements of the snout, circling, and even locomotion (Sahibzada, Dean et al, 1986).…”

Section: Orienting the Tactile Fovea With The Superior Colliculusmentioning

confidence: 99%

See 1 more Smart Citation

The Robot Vibrissal System: Understanding Mammalian Sensorimotor Co-ordination Through Biomimetics

Prescott

Mitchinson

Lepora

et al. 2015

Sensorimotor Integration in the Whisker System

View full text Add to dashboard Cite

SummaryWe consider the problem of sensorimotor co-ordination in mammals through the lens of vibrissal touch, and via the methodology of embodied computational neuroscienceÑusing biomimetic robots to synthesize and investigate models of mammalian brain architecture. The chapter focuses on five major brain sub-systems and their likely role in vibrissal system functionÑsuperior colliculus, basal ganglia, somatosensory cortex, cerebellum, and hippocampus. With respect to each of these we demonstrate how embodied modelling has helped elucidate their likely function in the brain of awake behaving animals. We also demonstrate how the appropriate co-ordination of these sub-systems, with a model of brain architecture, can give rise to integrated behaviour in a life-like whiskered robot.

show abstract

Section: A Control Architecture For Behavioural Integration In Vibrismentioning

confidence: 99%

Section: Orienting the Tactile Fovea With The Superior Colliculusmentioning

confidence: 99%

The Robot Vibrissal System: Understanding Mammalian Sensorimotor Co-ordination Through Biomimetics

Prescott

Mitchinson

Lepora

et al. 2015

Sensorimotor Integration in the Whisker System

View full text Add to dashboard Cite

show abstract

“…More specifically, we tested the accuracy of saccades after a brief electrical microstimulation is applied in the deep superior colliculus (dSC) before the saccade onset. The dSC is a brainstem structure at the interface between the sensory systems and the saccade premotor centers in the PMRF (Hall and Moschovakis, 2004;Gandhi and Katnani, 2011). Its microstimulation induces a saccade for which the gaze compensates when applied before saccades toward a static target (Sparks et al, 1983).…”

Section: Introductionmentioning

confidence: 99%

Saccadic Interception of a Moving Visual Target after a Spatiotemporal Perturbation

Filippi¹,

Goffart²

2012

J. Neurosci.

View full text Add to dashboard Cite

Animals can make saccadic eye movements to intercept a moving object at the right place and time. Such interceptive saccades indicate that, despite variable sensorimotor delays, the brain is able to estimate the current spatiotemporal (hic et nunc) coordinates of a target at saccade end. The present work further tests the robustness of this estimate in the monkey when a change in eye position and a delay are experimentally added before the onset of the saccade and in the absence of visual feedback. These perturbations are induced by brief microstimulation in the deep superior colliculus (dSC). When the microstimulation moves the eyes in the direction opposite to the target motion, a correction saccade brings gaze back on the target path or very near. When it moves the eye in the same direction, the performance is more variable and depends on the stimulated sites. Saccades fall ahead of the target with an error that increases when the stimulation is applied more caudally in the dSC. The numerous cases of compensation indicate that the brain is able to maintain an accurate and robust estimate of the location of the moving target. The inaccuracies observed when stimulating the dSC that encodes the visual field traversed by the target indicate that dSC microstimulation can interfere with signals encoding the target motion path. The results are discussed within the framework of the dual-drive and the remapping hypotheses.

show abstract

“…[17,18]) with increasingly rich behavioural data (e.g. [3,4]) from small mammals, and taking advantage of ongoing interest in models of oculomotor control [19]. This may quickly uncover to what degree snout movements of small tactile mammals are akin, in nature and/or substrate, to saccadic movements in visual mammals, perhaps offering a robust and accessible comparative model to sit alongside the oculomotor system.…”

Section: Discussionmentioning

confidence: 99%