Motor Activity and Depression Severity in Adolescent Outpatients

Finazzi, Maria Eliza Pupo; Mesquita, Maria Eugênia; Lopes, Jair; Oliveira, Monicke; Porto, José Alberto Del

doi:10.1159/000262178

Cited by 23 publications

(17 citation statements)

References 69 publications

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“…Hence, our study is the first one demonstrating that MCI subjects have lower motor activity level compared to healthy controls, while carrying out IADLs and motor tasks in a clinical setting. Even though, it has been previously shown that depression is often associated with decreased motor activity [11][12][13][40][41][42], we did not find any association between depressive symptoms in MCI subjects and motor activity. In the present study, depressive symptoms, as measured by GDS and MADRS scores, were more frequently observed in MCI subjects than in healthy controls.…”

Section: Discussioncontrasting

confidence: 99%

Actigraphic Motor Activity in Mild Cognitive Impairment Patients Carrying Out Short Functional Activity Tasks: Comparison between Mild Cognitive Impairment with and without Depressive Symptoms

Yakhia

König

Flier

et al. 2014

JAD

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Section: Discussioncontrasting

confidence: 99%

Actigraphic Motor Activity in Mild Cognitive Impairment Patients Carrying Out Short Functional Activity Tasks: Comparison between Mild Cognitive Impairment with and without Depressive Symptoms

Yakhia

König

Flier

et al. 2014

JAD

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“…In support of Aim 1, MPI Walther showed that overall gross motor activity, as measured by wrist actigraphy, is reduced in acutely depressed individuals [27,55] and stable over 1 week [56]. This replicates other studies of MDD across the lifespan (youth, late life) [57][58][59][60]. As a preliminary test of whether this deficit continues into remission, MPI Walther examined actigraphy levels of 22 MDD patients during treatment.…”

Section: Actigraphy In Depressionsupporting

confidence: 60%

An Examination of Psychomotor Disturbance in Current and Remitted MDD: An RDoC Study

Shankman

Mittal

Walther

2020

J Psychiatry Brain Sci

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Major depressive disorder (MDD) is a serious public health problem that has, at best, modest treatment response-potentially due to its heterogeneous clinical presentation. One way to parse the heterogeneity is to investigate the role of particular features of MDD, an endeavor that can also help identify novel and focal targets for treatment and prevention efforts. Our R01 focuses on the feature of psychomotor disturbance (e.g., psychomotor agitation (PmA) and retardation (PmR)), a particularly pernicious feature of MDD, that has not been examined extensively in MDD. Aim 1 is comparing three groups of individuals-those with current MDD (n = 100), remitted MDD (n = 100), and controls (n = 50)-on multiple measures of PmR and PmA (assessed both in the lab and in the subjects' natural environment). Aim 2 is examining the structural (diffusion MRI) and functional (resting state fMRI) connectivity of motor circuitry of the three groups as well as the relation between motor circuitry and the proposed indicators of PmR and PmA. Aim 3 is following up with subjects three times over 18 months to evaluate whether motor symptoms change in tandem with overall depressive symptoms and functioning over time and/or whether baseline PmR/PmA predicts course of depression and functioning. Aim 3 is particularly clinically significant. Finding that motor functioning and overall depression severity co-vary over time, or that motor variables predict subsequent change in overall depression severity, would support the potential clinical utility of these novel, reliable, and easily administered motor assessments.

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“…The definition of the low-intensity activities is an important issue in the present study. The threshold of sedentary or low activities varied from 20 to 200 [ 13 , 30 – 32 ], probably due to the differences of the measuring method, the definition of low activity, or the investigation population. We defined actigraphic counts less than 40 per minute as low-intensity activities based on the report of Wilson et al [ 13 ], however, the mean activity counts and the peak activity counts of our participants were considerably lower than those of the participants in Wilson’s report.…”

Section: Discussionmentioning

confidence: 99%

Physical activity of elderly patients with rheumatoid arthritis and healthy individuals: an actigraphy study

Hashimoto

Yoshiuchi

Inada

et al. 2015

BioPsychoSocial Med

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BackgroundMost people with rheumatoid arthritis (RA) are physically inactive. An accelerometer worn on the waist has been used to evaluate physical activity in people with chronic conditions. It is useful for evaluating moderate to vigorous activity, although it tends to underestimate light or mild activities such as housework or family duties. An accelerometer worn on the wrist (i.e., actigraph) has recently been used to capture daily physical activity in inactive individuals. The purposes of this study were to investigate physical activity measured by an actigraph in patients with RA and in healthy individuals and to investigate the association between actigraphic data and self-reported physical function.MethodsThe subjects were 20 RA patients and 20 healthy individuals. All participants wore an actigraph on their wrist for 6–7 consecutive days. They also completed the Health Assessment Questionnaire disability index (HAQ-DI) and the Medical Outcomes Study (MOS) 36-item short form health survey (SF-36). We extracted three parameters from the actigraphic data: mean activity count (MAC), peak activity count (PAC), and low activity ratio (LAR). These three parameters were compared between the RA patients and healthy individuals and with the self-reported questionnaires.ResultsThe MAC was significantly lower and the LAR was significantly higher in RA patients than in healthy individuals. The PAC was not different between the two groups. The LAR was negatively correlated with the MAC for the RA patients and for the healthy individuals. The decrease ratio of the LAR with the increase of the MAC for the RA patients was twice that of the healthy participants. In the RA patients, the LAR was significantly and moderately correlated with the HAQ-DI score and two dimensions of the SF-36 (i.e., “physical functioning” and “bodily pain”).ConclusionInvestigation of the proportion of low activity count using an actigraph may be useful to identify characteristics of the physical function in RA patients.

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Motor Activity and Depression Severity in Adolescent Outpatients

Cited by 23 publications

References 69 publications

Actigraphic Motor Activity in Mild Cognitive Impairment Patients Carrying Out Short Functional Activity Tasks: Comparison between Mild Cognitive Impairment with and without Depressive Symptoms

Actigraphic Motor Activity in Mild Cognitive Impairment Patients Carrying Out Short Functional Activity Tasks: Comparison between Mild Cognitive Impairment with and without Depressive Symptoms

An Examination of Psychomotor Disturbance in Current and Remitted MDD: An RDoC Study

Physical activity of elderly patients with rheumatoid arthritis and healthy individuals: an actigraphy study

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