Motivation and attention following hemispheric stroke

Olgiati, Elena; Russell, Charlotte; Soto, David; Malhotra, Paresh

doi:10.1016/bs.pbr.2016.06.011

Cited by 14 publications

(9 citation statements)

References 90 publications

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“…As this change was not selective to a given region of space, a general effect of heightened arousal and motivation might have contributed to improving search efficiency in addition to, or independently from, spatially-specific effects of training on search direction. Enhanced arousal in a reward context is plausible since it has been reported that subliminal processing of reward cues is associated with increased skin conductance responses, generally considered to reflect increased basal forebrain dopaminergic and noradrenergic activation (Pessiglione et al, 2007, Olgiati et al, 2016.…”

Section: Discussionmentioning

confidence: 99%

Following the gold trail: Reward influences on spatial exploration in neglect

Neppi-Mòdona

Sirovich

Cicerale

et al. 2020

Cortex

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Spatial attention is guided by the perceived salience and relevance of objects in the environment, a process considered to depend on a broad parieto-frontal cortical network. Signals arising from the limbic and nigrostriatal pathways conveying affective and motivational cues are also known to modulate visual selection, but the nature of this contribution and its relation to spatial attention remain unclear. We investigated the role of reward information in 15 patients with left hemispatial neglect and 15 control subjects playing multiple rounds of a virtual foraging game. Participants' exploration tracked dynamically adjusted underlying reward distributions, largely unbeknownst to them. Both control and neglect participants showed typical exploration/exploitation balance dependent on abundance or scarcity of rewards. De-reinforcing previously favored, mostly right, regions of space attenuated left space under-exploration in patients. Multiple regression analysis indicates that such reward-based training may benefit mostly patients early after lesion onset, with mild neglect and small lesions sparing subcortical regions. Our findings support the view that spatial exploration recruits heavily right hemispheric visuospatial attentional mechanisms as well as reward signals processed by basal ganglia and prefrontal cortical circuits, which serve to learn about the motivational relevance of environmental stimuli and help prioritize attention and motor response selection.

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Section: Discussionmentioning

confidence: 99%

Following the gold trail: Reward influences on spatial exploration in neglect

Neppi-Mòdona

Sirovich

Cicerale

et al. 2020

Cortex

View full text Add to dashboard Cite

show abstract

“…Finally, Della Libera and Chelazzi (2009) demonstrated not only that attentional processes are influenced by rewards but also that this effect is long-lasting, occurring several days after the end of the learning phase and when rewards are no longer at stake. These data open interesting perspectives for rehabilitation of patients with attention disorders (see Lucas et al, 2013;Olgiati et al, 2016) or abnormal reward-seeking behaviors (see Anderson et al, 2013a).…”

Section: Figmentioning

confidence: 99%

“…Likewise, Lecce et al (2015) demonstrated in a spatial reward-learning task that despite defective allocation of attention toward the contralesional left hemispace, right brain-damaged patients with neglect showed preserved contralesional reward learning compared to right brain-damaged patients without neglect. A more detailed review of this topic is provided by Olgiati et al (2016).…”

Section: Reward Effects In Neglect Patientsmentioning

confidence: 99%

How motivation and reward learning modulate selective attention

Bourgeois

Chelazzi

Vuilleumier

2016

Progress in Brain Research

107

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“…Additionally, motivational deficits, which make neglect patients extremely difficult to rehabilitate, may also play key roles in patients’ sustained attention deficits. Recent intervention work has highlighted how reward contingencies and playing rewarding music can improve both spatial and nonspatial symptoms of neglect . Current research is focused on elucidating the mechanisms of these sustained attention deficits and how they exacerbate spatial biases and impede recovery.…”

Section: Deficits In Sustained Attention Ability: Clinical Populationsmentioning

confidence: 99%

“…Recent intervention work has highlighted how reward contingencies and playing rewarding music can improve both spatial and nonspatial symptoms of neglect. 158,159 Current research is focused on elucidating the mechanisms of these sustained attention deficits and how they exacerbate spatial biases and impede recovery.…”

Section: Deficits In Sustained Attention Ability: Clinical Populationsmentioning

confidence: 99%

Recent theoretical, neural, and clinical advances in sustained attention research

Fortenbaugh

DeGutis

Esterman

2017

Annals of the New York Academy of Sciences

205

161

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Models of attention often distinguish between attention subtypes, with classic models separating orienting, switching, and sustaining functions. Compared to other forms of attention, the neurophysiological basis of sustaining attention has received far less attention yet it is known that momentary failures of sustained attention can have far ranging negative impacts in healthy individuals and lasting sustained attention deficits are pervasive in clinical populations. In recent years, however, there has been increased interest in characterizing moment-to-moment fluctuations in sustained attention in addition to the overall vigilance decrement and understanding how these neurocognitive systems change over the lifespan and across various clinical populations. The use of novel neuroimaging paradigms and statistical approaches has allowed for better characterization of the neural networks supporting sustained attention, and highlighted dynamic interactions within and across multiple distributed networks that predict behavioral performance. These advances have also provided potential biomarkers to identify individuals with sustained attention deficits. These findings have led to new theoretical models of why sustaining focused attention is a challenge for individuals and form the basis for the next generation of sustained attention research, which seeks to accurately diagnose and develop theoretically-driven treatments for sustained attention deficits that affect a variety of clinical populations.

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Motivation and attention following hemispheric stroke

Cited by 14 publications

References 90 publications

Following the gold trail: Reward influences on spatial exploration in neglect

Following the gold trail: Reward influences on spatial exploration in neglect

How motivation and reward learning modulate selective attention

Recent theoretical, neural, and clinical advances in sustained attention research

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