Motion-onset VEPs reflect long maturation and early aging of visual motion-processing system

Abstract

Pattern-reversal and motion-onset visual evoked potentials (VEPs) were simultaneously tested in a group of 70 healthy subjects between the ages of 6-60 years to verify suspected differences in maturation and aging dynamics of the pattern and motion processing subsystems of the visual pathway. The motion-onset VEPs displayed dramatic configuration development and shortening of latencies up to 18 years of age (correl. coeff. -0.85; p < 0.001) and systematic prolongation from about 20 years of age (correl. coeff. 0.70; p < 0.001). This confirms long-lasting maturation of the magnocellular system and/or motion processing cortex and their early age related changes. Less significant changes of pattern-reversal VEPs in the tested age range can be interpreted as a sign of early maturation of the parvocellular system and its enhanced functional endurance in the elderly.

Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders

“…This is consistent with different maturation of electrophysiological markers of visual sensory detection (Langrova, Kuba, Kremlacek, Kubova, & Vít, 2006) and corresponds to the deviance detection in the auditory domain. A recent meta-analysis showed that deviance processing in the auditory modality is not a uniform process as it is more deteriorated in case of duration deviants than for frequency deviants and probably not changed for intensity deviants 5 They also compared the normal children group with children that have mental retardation; those results are discussed in Developmental disorders section of this article.…”

Normative data of Visual Evoked Potential in children and correlation with age

“…All components follow a signifi cant decrease in latency with age, reaching their adult values around 7-12 months. Langrova et al 13 have mentioned that maturation of the fl ash VEPs and pattern-related VEPs fi nish by 6 years of age.…”

Normal sensory and absent cognitive electrophysiological responses in functional visual loss following chemical eye burn

“…5). The only significant difference between the eyes appeared surprisingly in latencies of the motion-onset VEPs, where the originally affected eye displayed two prolonged latencies out of four variants of motion-onset VEPs in the second examination (related to the first examination) compared with our age-related norm [14] (see Table 1) and also in inter-ocular comparison (Fig. 4).…”

“…Upper limits of normal values of the evaluated latencies are defined as the average ?2.5 SD (corresponding to 99th percentile of the normal group estimate) and they are corrected for the particular age [14]. For the pattern-reversal and motion-onset responses, the normal group consisted of 70 subjects …”