Motion corrected free‐breathing delayed‐enhancement imaging of myocardial infarction using nonrigid registration

Image quality in magnetic resonance imaging (MRI) is considerably affected by motion. Therefore, motion is one of the most common sources of artifacts in contemporary cardiovascular MRI. Such artifacts in turn may easily lead to misinterpretations in the images and a subsequent loss in diagnostic quality. Hence, there is considerable research interest in strategies that help to overcome these limitations at minimal cost in time, spatial resolution, temporal resolution, and signal-to-noise ratio. This review summarizes and discusses the three principal sources of motion: the beating heart, the breathing lungs, and bulk patient movement. This is followed by a comprehensive overview of commonly used compensation strategies for these different types of motion. Finally, a summary and an outlook are provided.

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“…This has been applied to delayed enhanced cardiac MRI, 79 as well as to wholeheart coronary MRA 80 to our knowledge.…”

Section: -72mentioning

confidence: 99%

Motion Compensation Strategies in Magnetic Resonance Imaging

Heeswijk

Bonanno

Coppo

et al. 2012

Crit Rev Biomed Eng

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“…Using a model that incorporates regional scar thickness to estimate VT excitation wavefront propagation, the VT circuit isthmus was predicted and shown to overlap the actual isthmus, observed by electrical mapping, by around 90%. Although these experimental studies use signifi cantly higher-resolution DEMRI maps than what is currently acquired clinically, methods to obtain higher-resolution scar images in patients are being developed [32]. Together with studies to identify safe MRI protocols for patients with implanted defi brillators [33] and clinical correlation of DEMRI scar morphology to successful VT ablation sites, the role of MRI for clinical VT ablation will be better defi ned.…”

Section: Delayed-enhancement Mri For Vt Ablation Planningmentioning

confidence: 98%

MRI for electrophysiology

Kolandaivelu

Halperin

2009

curr cardiovasc imaging rep

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“…A similar approach has also been validated for ECG-triggered, free-breathing DE-MR imaging during a single cardiac phase. 29,30 Another tactic is to use a respiratory-triggered, segmented SSFP sequence, which eliminates the breath-hold requirement in cine SSFP and has been validated in healthy volunteers and sedated children. 31 A recent study in adult patients showed that the LV functional values obtained with this respiratory-triggered free-breathing SSFP technique are in good agreement with the results obtained with a breath-hold SSFP sequence (Fig.…”

Section: Free-breathing Cine Techniquesmentioning

confidence: 99%

Cardiac Magnetic Resonance Imaging for the Investigation of Cardiovascular Disorders. Part 2: Emerging Applications

Goenka¹,

Wang²,

Flamm³

2014

Texas Heart Institute Journal

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Cardiac magnetic resonance imaging has emerged as a robust noninvasive technique for the investigation of cardiovascular disorders. The coming-of-age of cardiac magnetic resonance-and especially its widening span of applications-has generated both excitement and uncertainty in regard to its potential clinical use and its role vis-à-vis conventional imagC ardiac magnetic resonance imaging (CMR) is unique in its ability to provide comprehensive evaluation of cardiovascular disorders in a single session. Part 1 of this review highlighted the mainstream applications of CMR that are now routinely used for diagnosis, risk stratification, and case management.1 In this section, we provide an overview of the principles and potential applications of emerging CMR techniques that seek to characterize the myocardial substrate in both health and disease. These techniques offer the ability to noninvasively delineate pathophysiologic processes in vivo and, therefore, to expand our understanding of cardiovascular disorders. We also present a synopsis of innovative applications of validated CMR techniques that have the potential to expand the usefulness of CMR as a clinically relevant, cost-effective tool for reliable investigation and accurate case management in a wide variety of clinical situations. T1 Mapping and Extracellular Volume QuantificationDetection of regional or replacement myocardial fibrosis on CMR arises from the visual evaluation of well-delineated areas of late gadolinium enhancement (LGE) on delayed-enhancement MR (DE-MR) imaging. As discussed in Part 1 of this review, 1 high contrast-to-noise ratio in DE-MR imaging is achieved by suppressing the signal from the normal, unaffected myocardium. However, in patients with diffuse interstitial fibrosis, defining the unaffected myocardium can be difficult, which limits the usefulness of DE-MR imaging for detecting diffuse myocardial processes and for quantifying the extent of extracellular matrix (ECM) expansion. Therefore, direct quantification of longitudinal relaxation time of tissue (T1) has been proposed as a novel alternative imaging biomarker of myocardial fibrosis.Depending on the composition of the tissue, T1 relaxation times vary across tissue types. Deviation from established ranges can therefore be used to quantify the effects of pathologic processes.2 The generation of parametric maps that encode T1 value in each pixel of an image is called T1 mapping (Fig. 1).Not only does T1 mapping provide quantitative estimation of diffuse myocardial disease processes and extracellular volume (ECV), but it has the advantage (when compared with DE-MR imaging) of circumventing the influences of windowing, of variations in signal enhancement, and of variability of observer input in characterizing the diseased myocardium.3 Recent robust developments in acquisition and postprocessing techniques have given T1 mapping significant traction.

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Motion corrected free‐breathing delayed‐enhancement imaging of myocardial infarction using nonrigid registration

Cited by 72 publications

References 23 publications

Motion Compensation Strategies in Magnetic Resonance Imaging

Motion Compensation Strategies in Magnetic Resonance Imaging

MRI for electrophysiology

Cardiac Magnetic Resonance Imaging for the Investigation of Cardiovascular Disorders. Part 2: Emerging Applications

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