Abstract:Imaging and characterizing the dynamics of cellular adhesion in blood samples is of fundamental importance in understanding biological function.In vitromicroscopy methods are widely used for this task, but typically require diluting the blood with a buffer to allow for transmission of light. However whole blood provides crucial mechanical and chemical signaling cues that influence adhesion dynamics, which means that conventional approaches lack the full physiological complexity of living microvasculature. We p… Show more
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