Mothers' Experiences of Caring for Children Receiving Growth Hormone Treatment

<p>Exploring Potentially Modifiable Factors That Influence Treatment Non-Adherence Amongst Pediatric Growth Hormone Deficiency: A Qualitative Study</p>

“…Within our study, participants highlighted the physical burdens experienced during the administration process, focusing primarily on the burdens of the device. As has been reported in previous qualitative literature, 35,37,38 participants reported to experiencing complications with the device features, difficulties with the technical handling of the device, and tensions with the physical consequence of the injection for their child, namely the pain and discomfort. These burdens, in turn, had been a source of frustration and apprehension for the participants, thus in turn, impacting upon their treatment behavior.…”

“…The analytical orientation was pre-determined by prior knowledge from a recently conducted systematic review 22 and previous comparable literature. [35][36][37][38][39] The analyst's interpretation within the current thematic analysis was guided by a specific focus on the research objective to specifically explore the potentially modifiable factors that influence treatment non-adherence amongst parents/caregivers of children with GHD, although the analyst was open to new contextual ideas and concepts within the raw data. The intention of the analyst was to explore and integrate the diverse views, perspectives, and experiences of the participants and comprehensively report the semantic reality of participants.…”

“…[34][35][36] Many children are diagnosed and prescribed rhGH treatment from early childhood, which requires parents/caregivers to assume the undertaking of the daily injection administration. 35,37 Parents/caregivers commonly face a number of increased challenges for the first years of rhGH treatment, and often further into the child's teenage and young adult years. [35][36][37][38][39] Thus, a key way to better understanding the complex issue of pediatric non-adherence to rhGH treatment is to explore the personal perspectives of the parent/caregiver.…”

“…Several qualitative studies have explored factors relating to treatment non-adherence, among various clinical indications for rhGH treatment. [35][36][37][38] There has been limited evidence, however, with regard to the factors that influence non-adherence specifically amongst parents/caregivers of children with GHD. Thus, in light of the findings from the recent systematic review 22 and supporting literature, 4,7,8,15,40,41 the aim of this qualitative study was to specifically explore the potentially modifiable factors that influence non-adherence to rhGH treatment amongst parents/caregivers of children with GHD.…”

What Potentially Modifiable Factors are Associated With Treatment Nonadherence in Pediatric Growth Hormone Deficiency? A Quantitative Study

“…Given the overall implications of non-adherence on GHD patients and their families, healthcare professionals and the health care system, it is evident that treatment nonadherence is an important health issue, that warrants further attention [4,8,[25][26]. In view of the findings from the systematic review [10] and surrounding rhGH literature [1][2][3][4][5][11][12][13][27][28][29][30][31][32][33][34], the key objectives of the current study were to: determine the prevalence rate of nonadherence to rhGH treatment in paediatric GHD, examine the contribution of parental illness beliefs, treatment beliefs and the perceived HCP-parent/caregiver relationship on treatment adherence and in doing so, identify the potentially modifiable factors associated with nonadherence to rhGH treatment.…”