Mosquitocidal and Oviposition Repellent Activities of the Extracts of Seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus

Yu, Ke-Xin; Wong, Ching-Lee; Raza, Ahmad; Jantan, Ibrahim

doi:10.3390/molecules200814082

Cited by 26 publications

(17 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this regard, Rajkumar and Jebanesan (2009) have reported the oviposition deterrence effects of the extracts of Cassia obtusifolia with repellency at higher concentration (400 mg/L). The present study results are favourably supported by the oviposition deterrent activity of Bryopsis pinnata investigated by Yu et al (2015). He determined the oviposition deterrent activity viz., hexane, chloroform, methanol and aqueous extract of B. pinnata.…”

Section: Discussionsupporting

confidence: 72%

“…Currently, several studies report the use of seaweed extracts as mosquito Ovicidal, oviposition deterrent, and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India control agent against different mosquito species (Murugan et al, 2015;Kalimuthu et al, 2014;Kumar et al, 2012;Manilal et al, 2011). Yu et al (2015) gave a comprehensive review on the use of seaweed extracts and their bioactive components as mosquitocidal potential.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India

Veni

Pushpanathan²,

Mohanraj

2016

JES

View full text Add to dashboard Cite

The objective of the present study was to investigate the mosquito ovicidal, oviposition deterrent and larvicidal efficacy of hexane, benzene, chloroform, ethyl acetate and methanol extracts of, Lobophora variegata against malarial vector Anopheles stephensi. Among the five extract tested, the methanol extract was notable, which attained the 100 percent mortality at the concentration of 200.0 ppm and the hatchability rate ranged from 71.3 to 36.3 percent. In laboratory oviposition deterrent test, the extract of L. variegata greatly reduced the number of eggs deposited by gravid An. stephensi. The maximum and significant diminished fecundity in An. stephensi was observed with methanol extract which caused 76.15Ââ€“97.69% effective deterrence. Larvicidal response of An. stephensi was more susceptible in methanol extract. The LC50 Âvalue of methanol extract was 61.63 ppm and the Chi-square value were significant at p<0.05 level. It is concluded, that the extract ofÂ L. variegata could be used in control of malarial vector An. stephensi.

show abstract

Section: Discussionsupporting

confidence: 72%

Section: Introductionmentioning

confidence: 99%

Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India

Veni

Pushpanathan²,

Mohanraj

2016

JES

View full text Add to dashboard Cite

show abstract

“…With the increased interest in developing new mosquito repellents from natural products (NPs), essential oils are considered an interesting source due to their widely diverse class of volatile and low-molecular-weight compounds and also to their ovicidal, larvicidal, and repellent activities against human disease vectors. 22−26 With the resurgence of NPs in the development of new bioactive compounds by the pharmaceutical and cosmetic industries 27−30 and due to the cutting-edge technologies of combinatory chemistry, cheminformatics, and molecular modeling, new studies have focused on essential oils to explore their potentiality as mosquito repellents. 23,31,32 Recently, we have used different computational approaches to investigate biomolecular systems with emphasis on enzymatic reaction and inhibition.…”

Section: Introductionmentioning

confidence: 99%

Exploring the Potentiality of Natural Products from Essential Oils as Inhibitors of Odorant-Binding Proteins: A Structure- and Ligand-Based Virtual Screening Approach To Find Novel Mosquito Repellents

et al. 2019

View full text Add to dashboard Cite

Odorant-binding proteins (OBPs) are the main olfactory proteins of mosquitoes, and their structures have been widely explored to develop new repellents. In the present study, we combined ligand- and structure-based virtual screening approaches using as a starting point 1633 compounds from 71 botanical families obtained from the Essential Oil Database (EssOilDB). Using as reference the crystallographic structure of N,N-diethyl-meta-toluamide interacting with the OBP1 homodimer of Anopheles gambiae (AgamOBP1), we performed a structural and pharmacophoric similarity search to select potential natural products from the library. Thymol acetate, 4-(4-methyl phenyl)-pentanal, thymyl isovalerate, and p-cymen-8-yl demonstrated a favorable chemical correlation with DEET and also had high-affinity interactions with the OBP binding pocket that molecular dynamics simulations showed to be stable. To the best of our knowledge, this is the first study to evaluate on a large scale the potentiality of NPs from essential oils as inhibitors of the mosquito OBP1 using in silico approaches. Our results could facilitate the design of novel repellents with improved selectivity and affinity to the protein binding pocket and can shed light on the mechanism of action of these compounds against insect olfactory recognition.

show abstract

“…Research on seaweed-derived molecules has recently gained increased interest since they represent a source of diverse biologically active compounds. Importantly, insecticidal activities have been described from seaweed extracts [ 31 , 32 , 33 , 34 , 45 ]. Here we describe the potential larvicidal activity of extracts derived from L. dendroidea .…”

Section: Resultsmentioning

confidence: 99%

Larvicidal Potential of the Halogenated Sesquiterpene (+)-Obtusol, Isolated from the Alga Laurencia dendroidea J. Agardh (Ceramiales: Rhodomelaceae), against the Dengue Vector Mosquito Aedes aegypti (Linnaeus) (Diptera: Culicidae)

et al. 2016

View full text Add to dashboard Cite

Dengue is considered a serious public health problem in many tropical regions of the world including Brazil. At the moment, there is no viable alternative to reduce dengue infections other than controlling the insect vector, Aedes aegypti Linnaeus. In the continuing search for new sources of chemicals targeted at vector control, natural products are a promising alternative to synthetic pesticides. In our work, we investigated the toxicity of a bioactive compound extracted from the red alga Laurencia dendroidea J. Agardh. The initial results demonstrated that crude extracts, at a concentration of 5 ppm, caused pronounced mortality of second instar A. aegypti larvae. Two molecules, identified as (−)-elatol and (+)-obtusol were subsequently isolated from crude extract and further evaluated. Assays with (−)-elatol showed moderate larvicidal activity, whereas (+)-obtusol presented higher toxic activity than (−)-elatol, with a LC50 value of 3.5 ppm. Histological analysis of the larvae exposed to (+)-obtusol revealed damage to the intestinal epithelium. Moreover, (+)-obtusol-treated larvae incubated with 2 µM CM-H2DCFDA showed the presence of reactive oxygen species, leading us to suggest that epithelial damage might be related to redox imbalance. These results demonstrate the potential of (+)-obtusol as a larvicide for use against A. aegypti and the possible mode of action of this compound.

show abstract

Mosquitocidal and Oviposition Repellent Activities of the Extracts of Seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus

Cited by 26 publications

References 45 publications

Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India

Ovicidal, oviposition deterrent and larvicidal response of Anopheles stephensi Liston, 1901 to Lobophora variegata Lamouroux, 1817 from Tuticorin coast, Gulf of Mannar, India

Exploring the Potentiality of Natural Products from Essential Oils as Inhibitors of Odorant-Binding Proteins: A Structure- and Ligand-Based Virtual Screening Approach To Find Novel Mosquito Repellents

Larvicidal Potential of the Halogenated Sesquiterpene (+)-Obtusol, Isolated from the Alga Laurencia dendroidea J. Agardh (Ceramiales: Rhodomelaceae), against the Dengue Vector Mosquito Aedes aegypti (Linnaeus) (Diptera: Culicidae)

Contact Info

Product

Resources

About