Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS

Abstract

This study confirms that several readily-measured nutritional indicators predict mortality among hemodialysis patients and that changes in indicator values over six months provide additional important prognostic information. Interventions that modify these indicators of nutritional status may have an important impact on the survival of hemodialysis patients.

Diabetic Nephropathy in Type 2 Diabetes Prevention and Patient Management

“…Close follow-up of these patients is recommended to avoid malnutrition. The danger of malnutrition is illustrated by the fact that in dialysis patients low body mass index predicts poor survival (92).…”

Neutrophil to lymphocyte ratio in predicting short-term mortality in hemodialysis patients

“…Reddan and co-workers found an increased neutrophil number and reduced lymphocyte count to be independent predictors of mortality in hemodialysis patients (Reddan et al, 2003). The Dialysis Outcomes and Practice Pattern Study (DOPPS), an observational study of chronic hemodi- alysis patients showed lower baseline lymphocyte count and higher baseline and six-month increases in neutrophil count to be significantly associated with higher mortality (Pifer et al, 2002). Elevated white cell or neutrophil number was also found to be a significant predictor of all-cause and cardiac mortality in peritoneal dialysis (PD) patients, independent of clinical, biochemical, and inflammatory parameters (Johnson et al, 2005).…”

Body Mass Index-Mortality Paradox in Hemodialysis Patients

“…1 However, in hemodialysis patients, a number of clinical studies have demonstrated that BMI is inversely related to mortality. 2,3 The explanation for this interesting paradox is unknown.…”