Mortality Risk Factors in Descending Necrotising Mediastinitis

Deu-Martín, Maria; Sáez‐Barba, Manel; Sanz, Iker López; Peñarrocha, Rosa Alcaraz; Vielva, Laura Romero; Montserrat, Joan Solé

doi:10.1016/s1579-2129(10)70046-x

Cited by 37 publications

(44 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Isolated case reports or series with less than 4 cases of descending necrotizing mediastinitis, which have low evidence level (IV), were not included for the purpose of analysis in this review. Reports of descending necrotizing mediastinitis published before the year 2009 were also not included because there are reviews of accumulated cases from the period from 1969 to 1989, from 1970 to 1997, and from 1998 to 2008, along with 5 meta‐analysis of these periods; all other case series published between 2009 to 2014 were included …”

Section: Study Design: Systematic Review Of the Literaturementioning

confidence: 99%

Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description

2016

View full text Add to dashboard Cite

show abstract

Section: Study Design: Systematic Review Of the Literaturementioning

confidence: 99%

Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description

2016

View full text Add to dashboard Cite

show abstract

“…Lifestyle factors include smoking and excessive alcohol consumption 12. Mean age at presentation is 48–56 years 1 2 13…”

Section: Discussionmentioning

confidence: 99%

Taking heed of the ‘danger space’: acute descending necrotising mediastinitis secondary to primary odontogenic infection

Mark¹,

Song

Mark

2018

BMJ Case Reports

View full text Add to dashboard Cite

Descending necrotising mediastinitis (DNM) is an uncommon clinical entity which may arise secondary to primary odontogenic or neck infection in susceptible patients. Infection may spread contiguously via the alar or 'danger' space, a potential anatomical space posterior to the true retropharyngeal space. Spread of infection to the mediastinum almost always necessitates urgent cardiothoracic surgical intervention. This case report describes a male patient whose clinical deterioration following the diagnosis of submandibular abscess was investigated with CT imaging of the chest, where a diagnosis of DNM was made. Diagnosis was confirmed following surgical intervention and aspiration of pus from the mediastinum.

show abstract

“…Bu enfeksiyon desendan yol ile mediastene yayılarak DNM'ye neden olabilir. [2][3][4][5][6][7] Desendan nekrotizan mediastinit acil tanı ve tedavi gerektiren bir klinik tablodur. Hava yolu güvenliğinin sağlanması, geniş spektrumlu antibiyoterapi, drenaj ve debridman, kaynak kontrolü, hiperbarik oksijen tedavisi ve DNM komplikasyonlarının kontrolü tedavi protokolünü oluşturur.…”

Section: Discussionunclassified

“…Hava yolu güvenliğinin sağlanması, geniş spektrumlu antibiyoterapi, apse odaklarının drenaj ve debridmanı ve gerekirse yoğun bakım desteği tedavinin bileşenlerini oluşturur. [2][3][4][5] Servikal nekrotizan fasiit olgularının %40-45'inde negatif göğüs içi basınç nedeniyle mediastinal yayılım (desendan nekrotizan mediastinit; DNM) saptanır. [6,7] İlk kez Pearse tarafından 1938 yılında tanımlanan DNM'de SNF retrofarengeal alandan alar fasya aracılığıyla doğrudan arka mediastene veya karotis kılıf aracılığıyla ön mediastene ve perikarda yayılır.…”

unclassified

Descending necrotizing mediastinitis secondary to cervical necrotizing fasciitis: Two case reports and contemporary literature

Yılmaz¹

2017

Kulak Burun Bogaz Ihtis Derg

View full text Add to dashboard Cite

ÖZServikal nekrotizan fasiit, daha çok yaşlılarda ve immün yetmezliği bulunan hastalarda görülen, polimikrobiyal kökenli, hızlı ve yıkıcı seyreden ve bazen ölümcül olabilen bir derin boyun enfeksiyonudur. Nadiren enfeksiyon derin fasiyal planlar aracılığı ile mediastene yayılır ve desendan nekrotizan mediastenite neden olur. Desendan nekrotizan mediastinit yüksek mortaliteye sahip, acilen tanı konulup tedavi edilmesi gereken ciddi bir tablodur. Bu derlemede biri tip 1, diğeri de tip 2B desendan nekrotizan mediastinit tanısı ile servikal ve mediastinal drenaj ile tedavi edilmiş iki olgu sunuldu ve konu ile ilgili güncel literatür tartışıldı.Anahtar Sözcükler: Servikal nekrotizan fasiit; desendan nekrotizan mediastinit; mediastinoskopi; torakotomi. ABSTRACTCervical necrotizing fasciitis is a polymicrobial, rapidly progressive, destructive, and sometimes fatal deep neck infection, that is most commonly seen in the elderly and immunocompromised patients. The infection rarely spreads to mediastina via deep fascial planes and causes descending necrotizing mediastinitis. Descending necrotizing mediastinitis is a serious clinical entity with a high mortality rate that should be promptly diagnosed and treated. In this review, we present two cases with type 1 and type 2B descending necrotizing mediastinitis treated with servical and mediastinal drainage, and also discuss relevant contemporary literature.

show abstract

Mortality Risk Factors in Descending Necrotising Mediastinitis

Cited by 37 publications

References 22 publications

Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description

Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description

Taking heed of the ‘danger space’: acute descending necrotising mediastinitis secondary to primary odontogenic infection

Descending necrotizing mediastinitis secondary to cervical necrotizing fasciitis: Two case reports and contemporary literature

Contact Info

Product

Resources

About