Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009

Ilić, Milena; Radevic, Svetlana; Stefanovic, Vladimir; Cirkovic, Tatjana; Zurovac, Tamara; Savić, Bojana; Kovacevic, Vladan

doi:10.2298/vsp1302189i

Cited by 2 publications

(2 citation statements)

References 18 publications

(19 reference statements)

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“…The youngest patient in our series was 30 years-old male. Analysis of gender distribution demonstrated a predominance of males among OSCC cases, which followed global trends and previous studies [ 22 , 28 ]. This finding might not be unexpected concerning increased exposure to risk factors highlighted in a recent national survey.…”

Section: Discussionsupporting

confidence: 84%

“…According to the Serbian National Cancer Registry data, oral and pharyngeal cancer became the eight most common cancer types in males [ 22 – 25 ]. Recent studies in the Serbian population focused on an epidemiological aspect of OSCC in a limited number of patients, including mortality/morbidity rate trends, the detection of risk factors, and the economic aspect of treatment [ 22 , 24 , 26 – 28 ]. One study also investigated the OSCC’s histopathological profile [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

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Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study

Janović,

Bracanović,

Antić

et al. 2024

BMC Oral Health

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Background The mortality of oral squamous cell cancer (OSCC) in Serbia increased in the last decade. Recent studies on the Serbian population focused mainly on the epidemiological aspect of OSCC. This study aimed to investigate the demographic and imaging features of OSCC in the Serbian population at the time of diagnosis. Methods We retrospectively analyzed computed tomography (CT) images of 276 patients with OSCC diagnosed between 2017 and 2022. Age, gender, tumor site, tumor volume (CT-TV, in cm3), depth of invasion (CT-DOI, in mm), and bone invasion (CT-BI, in %) were evaluated. TNM status and tumor stage were also analyzed. All parameters were analyzed with appropriate statistical tests. Results The mean age was 62.32 ± 11.39 and 63.25 ± 11.71 for males and females, respectively. Male to female ratio was 1.63:1. The tongue (36.2%), mouth floor (21.0%), and alveolar ridge (19.9%) were the most frequent sites of OSCC. There was a significant gender-related difference in OSCC distribution between oral cavity subsites (Z=-4.225; p < 0.001). Mean values of CT-TV in males (13.8 ± 21.5) and females (5.4 ± 6.8) were significantly different (t = 4.620; p < 0.001). CT-DOI also differed significantly (t = 4.621; p < 0.001) between males (14.4 ± 7.4) and females (10.7 ± 4.4). CT-BI was detected in 30.1%, the most common in the alveolar ridge OSCC. T2 tumor status (31.4%) and stage IVA (28.3%) were the most dominant at the time of diagnosis. Metastatic lymph nodes were detected in 41.1%. Conclusion Our findings revealed significant gender-related differences in OSCC imaging features. The predominance of moderate and advanced tumor stages indicates a long time interval to the OSCC diagnosis.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study

Janović,

Bracanović,

Antić

et al. 2024

BMC Oral Health

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Analysis of Mortality from Carcinomas Primary Localized in Region of Lip, Oral Cavity and Pharynx in Central Serbia, 1999-2015

Stepovic¹,

Stajic²,

Sekulic³

et al. 2020

ijph

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Background: Lip, oral cavity, and pharyngeal cancers have been globally estimated to account for about 3.8% of all cancer cases and 3.6% of cancer deaths. Mortality of these cancers is generally higher in developing than in developed countries. Overall cancer mortality rate in Serbia is one of the highest in the world. The aim of this study was to determine the mortality rate trends and the most common localization of lip, oral and pharyngeal cancers in Serbia. Methods: The study was conducted in 2018 as descriptive epidemiological study and included years from 1999 to 2015. The differences in standardized mortality rates and number of deaths were analyzed with regard to age, gender, and tumor localization. Linear trend and regression were used to determine mortality rate trend. Results: There was statistically significant difference in the number of deaths between men and women in the ages of 40 and over (P < 0.01); male/female cancer mortality ratio was 4.56:1. Generally, the most common localization of this carcinoma was hypopharynx. There was no statistically significant increase of mortality rates from these cancers for both genders (males: y = 4.77 + 0.42x, P = 0.069 % change = +20.35; females: y = 1.03 + 0.01x, P = 0.40 % change = +4) during 17-year period. Conclusion: Promotion of healthy habits, life-styles and regular inspection of mouth by patients and health professionals should be better prioritized especially in developing countries where implementing and improving national health prevention programs are essential.

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Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009

Abstract: The increasing trend in lip, oral cavity and pharynx cancer mortality points to the necessity to investigate etiology and improve primary and secondary prevention measures.

Cited by 2 publications

References 18 publications

Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study

Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study

Analysis of Mortality from Carcinomas Primary Localized in Region of Lip, Oral Cavity and Pharynx in Central Serbia, 1999-2015

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