Traumatic brain injury (TBI) is a leading cause of acquired epilepsy. [1][2][3] Injury severity, 3 type, and location of the injury 4,5 are critical risk factors for epilepsy after TBI, but other characteristics and conditions, such as sex, age, genetics, 2 psychiatric co-morbidity, and preceding TBI 6 are all likely to influence the epileptogenic processes as well.Far from all contributions of personal traits are well understood.Perinatal adversities such as low birth weight, low gestational age at birth, low Apgar score, and being born small for gestational age are well-known risk factors for the development of epilepsy, 7-15 but the impact of these factors on the risk of epilepsy and other neurological conditions among persons who have suffered TBI has not previously been studied. Related studies on the cognitive sequelae following TBI suggested that recovery following TBI was attenuated in low birth weight children compared with normal birth weight children 16 and that children with underlying neurodevelopmental disorders experienced prolonged trajectories of mild TBI with respect to the severity of symptoms. 17 This suggests that such perinatal adversities may increase the brain's vulnerability to subsequent neurologic