Mortality prediction models for pediatric intensive care: comparison of overall and subgroup specific performance

Abstract

All models discriminated well, also in most subgroups including neonates, but had difficulties predicting mortality for patients >6 days at the PICU. In a western European setting both the PIM2(-ANZ06) or a recalibrated version of PRISM3-24 are suited for overall individualized risk prediction.

Pediatric Index of Mortality 2 as a predictor of death risk in children admitted to pediatric intensive care units in Latin America: A prospective, multicenter study

“…Visser et al reported that PIM2 showed a tendency to predict lower mortality than that observed in the younger patients [30]. Ciofi degli Atti also reported an inadequate calibration of the score in adolescents.…”

Early fluid accumulation in children with shock and ICU mortality: a matched case–control study

“…Reasons for ICU admission were grouped into respiratory distress/failure, hemodynamic instability and others. The Pediatric Index of Mortality 2 (PIM 2) score was used as the measure of illness severity at ICU admission and calculated retrospectively [18,19]. Respiratory failure was defined as the need for respiratory support (non-invasive or invasive ventilation), and shock was defined as need for vasopressor support (other than dopamine B5 mcg/kg/min) during the initial 24 h of admission.…”

Validación del índice pediátrico de mortalidad 2 (PIM2) en Argentina: un estudio prospectivo, multicéntrico, observacional

“…Área bajo la curva ROC= 0,8392. et al 20 evaluaron el funcionamiento de ambos puntajes y sus distintas versiones en un estudio multicéntrico en Dinamarca y encontraron que todos los modelos calibraron en forma adecuada para los pacientes egresados de la UCIP durante los primeros 6 días. En cambio, la mortalidad observada fue significativamente mayor que la predicha (RME > 1) en pacientes con estadía superior.…”