Mortality of Patients With Renal Dysfunction After Percutaneous Coronary Intervention

Abstract

In patients with ACS after PCI, a higher stage of renal dysfunction was directly associated with higher mortality of these patients.

A prospective study about impact of renal dysfunction and morbidity and mortality on cardiovascular events after ischemic stroke

“…In study by Tsagalis et al [13] including patients with acute stroke (ischemic stroke and intra-cerebral hemorrhage), the prevalence of renal dysfunction was 28%. Furthermore, the prevalence of renal dysfunction in patients with CVD is also higher than in general population, reported prevalence of renal dysfunction in patients with CHD is 18-37% [8,10,13,23]. In study by Koren-Morag et al [17], where patients with stable CVD were included, the prevalence of ischemic stroke or TIA was observed; the prevalence of renal dysfunction of included patients was 20%.…”

“…Patients with renal dysfunction are at increased risk of CVD and in some studies renal dysfunction was an independent risk factor for developing CVD including stroke [8,12,16,23,24]. In meta-analysis by Lee et al [16], renal dysfunction defined as eGFR < 60 mL/min/1.73 m 2 was independently related to incident ischemic and hemorrhagic stroke.…”

“…The main reason for high prevalence of CHD in patients with renal dysfunction is accelerated atherosclerosis, which starts already in early stages of renal failure [7]. Patients with earlier stages of CKD are not only at increased risk of CHD but have also a higher CV mortality compared to general population [1,2,4,8]. Furthermore, patients with CKD are more likely to die of CVD than to start with replacement therapy because of ESRD [9].…”

“…It was also shown that in patients with CHD the prevalence of renal dysfunction is higher than in general population and is estimated to be 18-37% [8,10]. Renal dysfunction was independently associated with an increased risk of death in patients with acute coronary syndrome (ACS) and was also strong and independent predictor of increased in--hospital and 1-year mortality after percutaneous coronary intervention [8,10].…”

“…Renal dysfunction was independently associated with an increased risk of death in patients with acute coronary syndrome (ACS) and was also strong and independent predictor of increased in--hospital and 1-year mortality after percutaneous coronary intervention [8,10].…”