Mortality of Iron Foundry Workers

Andjelkovich, Dragana A.; Shy, Carl M.; Brown, Michelle H.; Janszen, Derek B.; Levine, Richard J.; Richardson, Regina B.

doi:10.1097/00043764-199412000-00011

Cited by 41 publications

(18 citation statements)

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“…Some of the older studies used job title (often embalmers or pathologists) as a proxy for exposure (8, 14-17, 19, 21) or a more elaborate job exposure matrix (JEM) but focused on the last job held as indicated on the death certificate (27). Other methods included the use of (i) employment records (2,6,7,9,10,12,13,18,22,25,26), (ii) a JEM, (iii) industrial hygiene data (2,6,10,18,22,23,25,26), or (iv) selfreport of exposure to formaldehyde (11,20,24) or occupational history (23,28). Information on smoking, a key potential confounder, was available and accounted for in the analyses in only seven studies (6,11,20,22,24,25,28), some of which had large proportions of missing values for smoking variables.…”

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confidence: 99%

“…Information on smoking, a key potential confounder, was available and accounted for in the analyses in only seven studies (6,11,20,22,24,25,28), some of which had large proportions of missing values for smoking variables. Similarly, few studies had information on exposure to other occupational lung carcinogens that may be correlated with formaldehyde exposure (2,6,11,22,28). In addition, only six studies (2,13,16,20,21,29) included women in their study population, though analyses by gender were reported in only three studies (13,16,20).…”

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confidence: 99%

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Assessment of the effect of occupational exposure to formaldehyde on the risk of lung cancer in two Canadian population-based case–control studies

Mahboubi

Koushik²,

Siemiatycki³

et al. 2013

Scand J Work Environ Health

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confidence: 99%

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confidence: 99%

Assessment of the effect of occupational exposure to formaldehyde on the risk of lung cancer in two Canadian population-based case–control studies

Mahboubi

Koushik²,

Siemiatycki³

et al. 2013

Scand J Work Environ Health

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“…The SMRs were elevated in this study for the category that included molders, oven workers, casters, crane operators, and shake-out. A lung cancer SMR of 127 (107, 150) was reported from another follow-up study of iron foundry workers [Andjelkovich et al, 1990[Andjelkovich et al, , 1992. A statistically significant excess of lung cancer deaths was found for finishing and for general service and maintenance work areas.…”

Section: Discussionmentioning

confidence: 97%

“…If exposure to lung carcinogens at the facility were pervasive, then no particular job or departmental group would stand out as a special problem because, in essence, there is not an ''unexposed'' group. Cohort studies that have investigated specific work areas within foundries typically report elevated lung cancer SMRs in many areas within the foundry [Andjelkovich et al, 1992]. If lung carcinogens were widespread in this facility, null study finding would be anticipated.…”

Section: Discussionmentioning

confidence: 97%

“…A statistically significant excess of lung cancer deaths was found for finishing and for general service and maintenance work areas. However, the authors speculated that these findings reflected confounding by cigarette smoking since the excesses were not related directly to employment characteristics [Andjelkovich et al, 1992]. In a cohort study of about 600 molders in Danish metal foundries, a lung cancer SMR of 137 (63, 260) was reported [Hansen,1991].…”

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confidence: 99%

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A case-control study of lung cancer at a foundry and two engine plants

et al. 1997

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A nested case‐control study of lung cancer was conducted among workers at an iron foundry and two engine manufacturing plants whose lung cancer mortality rates were slightly higher than expected. The study included 231 lung cancer cases and 408 controls for whom complete work histories were obtained. There was no association between usual plant of employment and lung cancer mortality. The odds ratio for persons employed for 20 or more years in the foundry compared with persons employed in the engine plants was 0.90 (95% confidence interval: 0.55, 1.5). Long‐term employment as an engine plant worker was associated with odds ratios slightly, but not statistically significantly, below unity. In the foundry, only usual employment in the material handling departmental group and any employment in the quality control departmental group were statistically significantly directly related to lung cancer risk. However, the number of subjects so employed was small and there was no dose‐response relation between length of employment in these departmental groups and lung cancer risk. Cases were less frequently employed than were controls in engine plant machining and assembly jobs and departments. It is concluded that employment in this facility was either unrelated, or only weakly related, to lung cancer risk. Am. J. Ind. Med. 31:414–421, 1997. © 1997 Wiley‐Liss, Inc.

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Cancer risks among iron and steel workers in Anshan, China, part I: Proportional mortality ratio analysis

Zhao

Pan

et al. 1996

Am. J. Ind. Med.

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A standardized proportional mortality ratio (SPMR) study of 8,887 deaths during 1980–1989 among male workers in a large integrated iron‐steel complex in Anshan, China, was conducted to provide clues to occupational risk factors. Accidents and cancer accounted for a higher proportion of deaths among the iron‐steel workers than among the general male population (SPMR = 1.21; 95% CI = 1.12–1.31 and 1.14; 95% CI = 1.10–1.18, respectively). Among all workers, SPMRs were significantly elevated for stomach, lung, and colorectal cancers (SPMR = 1.37, 1.37, 1.38, respectively), but not other cancers. Risks of stomach cancer appeared to be highest among workers employed in jobs with exposure to iron and coal dust, whereas significant increases in colorectal cancer were seen for loading and other dusty jobs and for administrative and sedentary jobs without dust exposure. Risks of lung cancer appeared increased for a variety of jobs throughout the complex, especially those with probable high levels of exposure to polycyclic hydrocarbons and asbestos. Risk of esophageal cancer was significantly elevated for fire‐resistant brick makers, and risk of nonmalignant respiratory disease was significantly elevated for those employed as furnace workers, foundry workers, and fire‐resistant brick makers. (This article is a US Government work and, as such, is in the public domain in the United States of America.) © 1996 Wiley‐Liss, Inc.

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Mortality of Iron Foundry Workers

Cited by 41 publications

References 0 publications

Assessment of the effect of occupational exposure to formaldehyde on the risk of lung cancer in two Canadian population-based case–control studies

Assessment of the effect of occupational exposure to formaldehyde on the risk of lung cancer in two Canadian population-based case–control studies

A case-control study of lung cancer at a foundry and two engine plants

Cancer risks among iron and steel workers in Anshan, China, part I: Proportional mortality ratio analysis

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