Mortality in premature mice at birth and during neonatal development

Loctin, Jacqueline; Delost, P

doi:10.1051/rnd:19830213

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…But the clustering result indicates that the expression profile of E18.5 is more similar to those of time points after birth. It was reported that premature mice by caesarean section could not live if their gestational ages were less than 19 days [5]. While caesarean birth mice can survive and their weight handicaps in organs can be overcome in postnatal days [6].…”

Section: Resultsmentioning

confidence: 99%

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

Huang

Jiang

et al. 2009

Genomics

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The liver performs a number of essential functions for life. The development of such a complex organ relies on finely regulated gene expression profiles which change over time in the development and determine the phenotype and function of the liver. We used high-density oligonucleotide microarrays to study the gene expression and transcription regulation at 14 time points across the C57/B6 mouse liver development, which include E11.5 (embryonic day 11.5), E12.5, E13.5, E14.5, E15.5, E16.5, E17.5, E18.5, Day0 (the day of birth), Day3, Day7, Day14, Day21, and normal adult liver. With these data, we made a comprehensive analysis on gene expression patterns, functional preferences and transcriptional regulations during the liver development. A group of uncharacterized genes which might be involved in the fetal hematopoiesis were detected.

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Section: Resultsmentioning

confidence: 99%

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

Huang

Jiang

et al. 2009

Genomics

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“…To benefit maternal or fetal health, preterm cesarean delivery may be performed after either medically indicated or spontaneous preterm labor. To investigate the effect of cesarean delivery on fetal development and mortality, researchers surgically removed mouse fetuses before the normal delivery date and found that pups of the strain CD-1 could only be resuscitated when delivered on 19 or 20 dpc (20 dpc was the normal delivery time for this strain in their colony) [65], indicating that mice cannot survive outside the uterus if birth occurs more than 1 day preterm.…”

Section: Mouse Models Of Preterm Birthmentioning

confidence: 99%

Mouse models of preterm birth: suggested assessment and reporting guidelines†

McCarthy¹,

Martin-Fairey²,

Sojka

et al. 2018

Biology of Reproduction

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Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences. To investigate the mechanisms leading to preterm birth so as to develop prevention strategies, researchers have developed numerous mouse models of preterm birth. However, the lack of standard definitions for preterm birth in mice limits our field's ability to compare models and make inferences about preterm birth in humans. In this review, we discuss numerous mouse preterm birth models, propose guidelines for experiments and reporting, and suggest markers that can be used to assess whether pups are premature or mature. We argue that adoption of these recommendations will enhance the utility of mice as models for preterm birth.

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“…As the mortality of prematures has been studied carefully in primates, domestic animals and rodents (Loctin and Delost, 1983a) (Loctin, 1980 (Loctin, 1980 ;Loctin and Delost, 1983a (Loctin and Delost, 1983a) (Loctin, 1980 (Loctin, 1980) ; (2) there is a high loss of water and sodium in the first 6 neonatal hours in premature mice due to kidney immaturity (Loctin and Delost, 1982). Thus, omitting the weight of stomach milk, the body weight of full-term newborns increased by 2.5 % between birth and 6 h, whereas that of premature mice decreased by 4 %.…”

Section: Introductionmentioning

confidence: 99%

Somatic development in premature mice from birth to weaning

Loctin¹,

Delost²

1983

Reprod. Nutr. Dévelop.

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Summary. This paper reports a statistical and transversal study of After an early, transitory loss of body and organ weights, which occurred during the first neonatal day, the weight handicaps of premature mice were overcome before neonatal day 20 as follows : adrenal weight between 6 h and day 2, liver weight between days 2 and 6, kidney and body weights between days 6 and 20. Throughout these stages, the weight gain of body and organs was higher than that of full-term newborns. The weight gains of premature mice, like those of full-term newborns, were in inverse ratio to the number of newborns per litter. The role of some factors involved in the growth of organs of premature mice has been discussed and the somatic development of surviving premature mice has been compared to that of smallest premature human infants.Introduction.

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Mortality in premature mice at birth and during neonatal development

Cited by 3 publications

References 12 publications

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development

Mouse models of preterm birth: suggested assessment and reporting guidelines†

Somatic development in premature mice from birth to weaning

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