Mortality in high-risk patients with bleeding Mallory–Weiss syndrome is similar to that of peptic ulcer bleeding. Results of a prospective database study

Ljubičić, Neven; Budimir, Ivan; Pavić, Tajana; Bišćanin, Alen; Puljiz, Željko; Bratanić, Andre; Troskot, Branko; Zekanović, Dražen

doi:10.3109/00365521.2013.846404

Cited by 23 publications

(26 citation statements)

References 14 publications

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“… 41 , 42 A prospective study found that the 30-day mortality rate in Mallory-Weiss syndrome was 5.3%, similar to the mortality rate in peptic ulcer bleeding. 43 Clinically significant bleeding in Mallory-Weiss syndrome is associated with risk factors such as old age, coagulation disorders, underlying diseases such as portal hypertension, and active bleeding during endoscopic examination. Endoscopic hemostasis is necessary even in healthy patients without comorbidities when active bleeding, such as spurting or oozing, is observed during endoscopic examination.…”

Section: Bodymentioning

confidence: 99%

Guidelines for Nonvariceal Upper Gastrointestinal Bleeding

Kim

et al. 2020

Gut and Liver

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Nonvariceal upper gastrointestinal bleeding (NVUGIB) refers to bleeding that develops in the gastrointestinal tract proximal to the ligament of Treitz. NVUGIB requires hospitalization and is associated with significant morbidity and mortality. Although European and Asian-Pacific guidelines have been published, there have been no previous guidelines regarding management of NVUGIB in Korea. Korea has a high prevalence of Helicobacter pylori infections, and patients have easy accessibility to endoscopy. Therefore, we believe that guidelines regarding management of NVUGIB in Korea are essential. The Korean Society of Gastroenterology reviewed the recent evidence and recommends practical management guidelines on NVUGIB in Korea.

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Section: Bodymentioning

confidence: 99%

Guidelines for Nonvariceal Upper Gastrointestinal Bleeding

Kim

et al. 2020

Gut and Liver

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“…Mallory-Weiss tears (MWTs), characterized by mucosal lacerations in the region of the esophagogastric junction (EGJ), are a common cause of nonvariceal gastrointestinal bleeding. MWTs are usually caused by retching or forceful vomiting, and the reported incidence is as high as 15 % of all cases of acute upper gastrointestinal bleeding 1 2 3 . MWTs have also been recognized as an iatrogenic adverse event occurring during upper gastrointestinal endoscopic procedures, initially documented in 1976 4 .…”

Section: Introductionmentioning

confidence: 99%

Circumferential distribution and location of Mallory-Weiss tears: recent trends

et al. 2015

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Background and study aims: Mallory-Weiss tears (MWTs) are not only a common cause of acute nonvariceal gastrointestinal bleeding but also an iatrogenic adverse event related to endoscopic procedures. However, changes in the clinical characteristics and endoscopic features of MWTs over the past decade have not been reported. The aim of this study was to investigate recent trends in the etiology and endoscopic features of MWTs. Patients and methods: We retrospectively reviewed the medical records of patients with a diagnosis of MWT at our university hospital between August 2003 and September 2013. The information regarding etiology, clinical parameters, endoscopic findings, therapeutic interventions, and outcome was reviewed. Results: A total of 190 patients with MWTs were evaluated. More than half (n = 100) of the cases occurred during endoscopic procedures; cases related to alcohol consumption were less frequent (n = 13). MWTs were most frequently located in the lesser curvature of the stomach and right lateral wall (2 – to 4-o’clock position) of the esophagus, irrespective of the cause. The condition of more than 90 % of the patients (n = 179) was improved by conservative or endoscopic treatment, whereas 11 patients (5.8 %) required blood transfusion. Risk factors for blood transfusion were a longer laceration (odds ratio [OR] 2.3) and a location extending from the esophagus to the stomach (OR 5.3). Conclusions: MWTs were frequently found on the right lateral wall (2 – to 4-o’clock position) of the esophagus aligned with the lesser curvature of the stomach, irrespective of etiology. Longer lacerations extending from the esophagus to the gastric cardia were associated with an elevated risk for bleeding and requirement for blood transfusion.

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“…Massive hemorrhage is a leading cause of mortality . Resuscitation of massive hemorrhage has shifted toward earlier administration of plasma to reduce mortality .…”

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confidence: 99%