Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity

Guðmundsson, Gunnar; Gíslason, Þórarinn; Lindberg, Eva; Hallin, Runa; Ulrik, Charlotte Suppli; Brøndum, Eva; Nieminen, Markku M.; Aine, Tiina; Bakke, Per; Janson, Christer

doi:10.1186/1465-9921-7-109

Cited by 122 publications

(119 citation statements)

References 30 publications

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“…Kadın olgularda acile başvuru öncesi ilaç kullanı-mı oranı erkeklerden daha azdır (5). (14). Konjestif kalp yetmezliği ve kor pulmonale yaşam süresini etkileyen komorbiditelerdir (29).…”

Section: Discussionunclassified

“…Ottowa Risk Skalası puanları da birbirine benzerdi. Komorbitelerin mortaliteye etkisini araştıran başka bir çalışmada diyabetin akut atak nedeniyle hastaneye yatış sonrası mortaliteyi belirlemede önemli bir risk faktörü olduğu gösterilmiştir (14). Akut atak nedeni ile yoğun bakımda izlenen kadın ve erkek olgularımızda diyabet görülme sıklığı da benzerdi.…”

Section: Discussionunclassified

“…KOAH'lı hastalar akut atak sırasında yoğun bakıma yatırılarak tedavi edilebilmektedir. (14). Hastaneye yatışın gerekli olduğu ataklarda yaşam kalitesinde bozulma (12), akciğer fonksiyonlarında azalma (15) ve mortalite artışı (11), hastalığın doğal seyrini etkileyebilir.…”

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“…Kadınlar ve erkekler arasında KOAH akut atağındaki farklılıkları araştıran az sayıda çalışma bulunmaktadır (5,14). Kadınlarda acile baş-vuru öncesi ilaç kullanma oranı ve acile başvuru oranı daha düşüktür: İzlemde erkeklerin atakları daha uzun sürelidir ve atakların tekrarlama oranı daha fazladır.…”

unclassified

“…KOAH'ta atak döneminde algısal farklılıklar da olabilmektedir (5). Erkeklerde mortalite oranı daha fazladır (14). KOAH akut atağında kadın ve erkek hastalarda hastaneye yatış sırasındaki klinik özellikler ve uygulanan tedavilere ilişkin bir bilgi bulunmamaktadır.…”

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Effects of Gender on Physical, Physiological, and Clinical Characteristics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Yağlı¹,

Sağlam²,

İnce³

et al. 2015

Yoğun Bakim Derg

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Objective: Differences can be observed between genders in chronic obstructive pulmonary disease (COPD) arising from clinical, perceptual, and structural factors. The purpose of this study was to investigate the effects of gender on physical and physiological characteristics in acute exacerbation of COPD.Material and Methods: Seventy-one patients with acute exacerbation of COPD (44 males, 27 females) participated in this study. Physical and demographical characteristics, vital signs, admission findings, comorbidities, arterial blood gas values, and chest radiography findings were recorded. Level of consciousness was determined using the Glasgow coma scale. Acute Physiology and Chronic Health Evaluation II (APACHE II) score, acute physiology score, Charlson Comorbidity Index score, and Ottawa COPD Risk Scale score were calculated. Functional level was determined using the Functional Status Scale. Exercise capacity was analyzed. Treatments conducted for the subjects (medical treatment, respiratory support, and physiotherapy) were recorded.Results: Male and female subjects with acute exacerbation of COPD were similar in terms of age, signs and symptoms, chest radiography findings, exercise capacity, Charlson Comorbidity Index score, and Ottawa COPD Risk Scale score (p>0.05). Females' body mass index, APACHE II score, acute physiology score were significantly higher than those of males (p<0.05). The smoking history was significantly higher and functional capacity was lower in male subjects than in females (p<0.05). There were no significant differences in medical treatment, respiratory support, physiotherapy applications, and length of hospital stay between males and females (p>0.05) Conclusion: Male and female patients with acute exacerbation of COPD had physical, physiological, and clinical differences. Smoking history was low, and their participation in daily life activities was less impaired. Physiotherapy applications and other treatments performed were similar between females and males, despite a higher disease severity in females. (Yoğun Bakım Derg 2015; 6: 27-33 Bulgular: KOAH akut atağında olan erkek ve kadın olgularda yaş, semptom ve bulgular, akciğer radyografisi bulguları, egzersiz kapasitesi, Charlson Komorbidite İndeksi puanı, Ottawa KOAH Risk Skalası puanı birbirine benzerdi (p>0,05). Erkeklerin sigara öyküsü anlamlı olarak daha yüksek; fonksiyonel kapasite ise anlamlı olarak daha dü-şüktü (p<0,05). Kadınların vücut kitle indeksi, APACHE II puanı ve akut fizyoloji skoru, erkeklerden anlamlı olarak daha yüksekti (p<0,05). Erkek ve kadın bireyler arasında medikal tedavi, solunum desteği ve fizyoterapi uygulamaları ve hastanede kalış süresi açısından istatistiksel olarak anlamlı fark bulunmadı (p>0,05).Sonuç: KOAH akut atağında kadın ve erkek hastalar; fiziksel, fizyolojik ve klinik özellik-ler açısından farklılık göstermektedir. Kadınlarda sigara öyküsü daha azdır ve günlük yaşama katılımları daha iyidir. KOAH akut atağındaki kadın olguların hastalık şiddeti daha fazla olmasına rağmen, fizyoterapi uygula...

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Section: Discussionunclassified

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Effects of Gender on Physical, Physiological, and Clinical Characteristics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Yağlı¹,

Sağlam²,

İnce³

et al. 2015

Yoğun Bakim Derg

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Estimates of Medication Expenditure for Ischemic Heart Disease Accompanying Chronic Obstructive Pulmonary Disease

Rysiak

Prokop

Zaręba

et al. 2018

Advances in Experimental Medicine and Biology

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Ischemic heart disease (IHD) is a frequent accompaniment of chronic obstructive pulmonary disease (COPD). Co-occurrence of these two diseases is associated with many risk factors, difficulties in implementing appropriate therapies, numerous complications, and high spending for treatment. All these elements significantly reduce the quality of life of patients. The aim of this study was to estimate the expenditure for medications involved with IHD pharmacotherapy in the course of COPD. This retrospective study was based on the review of medical files of 57 patients, 27 women and 30 men, diagnosed with IHD, according to the severity classification, in the course of COPD which was staged according to the GOLD criteria. We found a considerable increase in per capita per year retail spending for drugs. The spending increased with the severity class of IHD; from 27.41 EUR in Class I to 142.30 EUR in Class IV. This spending did not include the treatment cost for the basic disease, i.e., COPD. A high individual cost burden was decreased by a discounting intervention of the National Health Fund. Despite a relatively high drug expenditure, we consider the treatment being cost-effective since we noticed a reduction in the classical risk factors for IHD, related to metabolic disturbances and lifestyle features, as soon as 2 months after treatment initiation. This study confirms that heart disease accompanying COPD is a frequent occurrence, generating high costs of treatment, which relates to the severity of this comorbidity.

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Management of Diabetes and Hyperglycemia in the Hospital Setting

DeMauro-Jablonski

Inzucchi

2009

Principles of Diabetes Mellitus

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Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity

Abstract: Mortality was high after COPD admission, with older age, decreased lung function, lower health status and diabetes the most important risk factors. Treatment with inhaled corticosteroids and long-acting bronchodilators may be associated with lower mortality in patients with COPD.

Cited by 122 publications

References 30 publications

Effects of Gender on Physical, Physiological, and Clinical Characteristics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Effects of Gender on Physical, Physiological, and Clinical Characteristics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Estimates of Medication Expenditure for Ischemic Heart Disease Accompanying Chronic Obstructive Pulmonary Disease

Management of Diabetes and Hyperglycemia in the Hospital Setting

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