“…Thermal stress associated with the heat waves during those warm years has directly, widely, and negatively affected animal life (61,80), including increased mortality of humans in geographically widespread regions (22,52,103). Globally, humans in heat waves have increased occurrence of disease (23,56,116,129) as well as heat-stroke-related mortality (129), the latter of which was recently observed during 2018 July heat waves in Japan and Canada (10). Hence, climate change-related increases in the frequency and severity of heat waves are a present threat to animal life, including humans, especially considering that urbanization increases the intensity of heat extremes (32), and most humans live in urbanized areas.…”