Mortality Associated with Incident Mental Health Disorders After Stroke

Almeida, Osvaldo P.; Xiao, Jianguo

doi:10.1080/00048670601172772

Cited by 72 publications

(64 citation statements)

References 23 publications

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“…This prevalence is higher than prevalence of 9.1% reported by Williams et al 37 , similar to 36.6% reported by Almeida et al 38 , but lower than 49-54.7% reported by other researchers [39][40] . All the other reports were from the developed countries.…”

Section: Discussionsupporting

confidence: 56%

Psychiatric morbidity in stroke patients attending a neurology clinic in Nigeria

Ajiboye¹,

Abiodun²,

Tunde-Ayinmode³

et al. 2013

Afr H. Sci.

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Back ground: Stroke produces a wide range of mental and emotional disorders. Neuropsychiatric complications associated with stroke may have negative effects on the social functioning, overall quality of life and the recovery of motor functioning of stroke survivors. Objective: To determine the prevalence and nature of psychiatric morbidity among stroke patients attending neurology outpatient clinic of the University of Ilorin Teaching Hospital (UITH), Ilorin-Nigeria. Methods: All patients with stroke aged 18 years and above at an outpatient neurology clinic in Ilorin, Nigeria were assessed for mental and emotional disorders using the Schedule for Clinical Assessment in Neuropsychiatry (SCAN) over one year (March 2009 to February 2010. Results: Overall prevalence of psychiatric morbidity was 36.0% (30/83) among 83 patients who constituted the study population. Specific diagnoses recorded were depression (19.2%), generalised anxiety disorder (9.6%), harmful alcohol use (2.4%); dementia, somatoform disorder, phobia and delusional disorder each had a prevalence of 1.2%. Clinical and sociodemographic variables were not significantly associated with psychiatric morbidity. Conclusion: Psychiatric disorders are often associated with stroke. Identifying and treating stroke patients with these psychiatric co-morbidities could thus help to improve the overall quality of life of these patients.

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Section: Discussionsupporting

confidence: 56%

Psychiatric morbidity in stroke patients attending a neurology clinic in Nigeria

Ajiboye¹,

Abiodun²,

Tunde-Ayinmode³

et al. 2013

Afr H. Sci.

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“…These included 134 outpatients with either schizophrenia (N ¼ 80, comprised of 61% women) or schizoaffective disorder (N ¼ 54, comprised of 48% women), and 123 HCs (comprised of 48% women) with no history of major neuropsychiatric illness. All the subjects were recruited from the greater San Diego community and interviewed using the Structured Clinical Interview for the DSM-IV-TR (SCID) (Almeida and Xiao, 2007). Subjects were excluded if they had 1) other current DSM-IV-TR Axis I diagnoses; 2) alcohol or other substance (other than tobacco) abuse or dependence within 3 months prior to enrollment; 3) diagnosis of dementia, mental retardation, or a major neurological disorder; 4) or any medical disability that interfered with their ability to complete the study assessments.…”

Section: Study Participantsmentioning

confidence: 99%

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Wolkowitz

Jeste

Martin

et al. 2017

Journal of Psychiatric Research

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a b s t r a c tBackground: Schizophrenia is linked with early medical comorbidity and mortality. These observations indicate possible "accelerated biological aging" in schizophrenia, although prior findings are mixed, and few such studies have examined the role of gender. One putative marker of biological aging is leukocyte telomere length (LTL), which typically shortens with age. Methods: We assessed LTL in phenotypically well characterized 134 individuals with schizophrenia (60 women and 74 men) and 123 healthy comparison subjects (HCs) (66 women and 57 men), aged 26 to 65 years. Results: Overall, LTL was inversely associated with age (t(249) ¼ -6.2, p < 0.001), and a gender effect on the rate of LTL decrease with age was found (t(249) ¼ 2.20, p ¼ 0.029), with men declining more rapidly than women. No significant overall effect of diagnosis on the rate of decline was detected. However, at the average sample age (48 years), there was a significant gender effect in both schizophrenia and HC groups (t(249) ¼ 2.48, p ¼ 0.014), with women having longer LTL than men, and a significant gender X diagnosis effect (t(249) ¼ 2.43, p ¼ 0.016) -at the average sample age, women with schizophrenia had shorter LTL than HC women. Discussion: Gender, not the diagnosis of schizophrenia, was the major factor involved with LTL shortening across the age range studied. We discuss the constraints of a cross-sectional design and other methodological issues, and indicate future directions. Understanding the impact of schizophrenia on biological aging will require separate evaluations in men and women.Published by Elsevier Ltd.

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“…Two hospital-registry studies identified only 0.4% 96 and 3.1% 97 of stroke patients with a psychotic disorder. The incidence was 1.11 per 1000 person-years, with gradual onset at an average of 6.1 months after stroke.…”

Section: Psychosis and Psychotic Symptomsmentioning

confidence: 99%

“…The incidence was 1.11 per 1000 person-years, with gradual onset at an average of 6.1 months after stroke. 97 Single psychotic symptoms not fulfilling criteria for syndromal psychotic disorder appear more common. For example, among patients admitted to somatic or rehabilitation wards of Dutch nursing homes, delusional symptoms were present in 3-10% of patients 68,77 and hallucinations in about 4%.…”

Section: Psychosis and Psychotic Symptomsmentioning

confidence: 99%

“…In a retrospective cohort study of 1008 stroke patients, psychosis was the only neuropsychiatric disorder significantly associated with a higher mortality rate, but why this should be specific to psychosis is obscure. 97 No prospective studies on the course and outcome of post-stroke psychosis are available. No clinical trial reported on prevention or treatment of psychosis after stroke.…”

Section: Psychosis and Psychotic Symptomsmentioning

confidence: 99%

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