Mortalité des patients avec une maladie rénale chronique stade 5 traités par suppléance

Jaı̈s, Jean-Philippe; Lobbedez, Thierry; Couchoud, Cécile

doi:10.1016/s1769-7255(22)00565-x

Cited by 4 publications

(3 citation statements)

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“…FOUDA reported a death rate of 58% after 15 months of follow-up (7). Jean-Philippe Jais reported a stable mortality rate in dialysis between 2008 and 2020 of 16 per 100 patient years in France (15). This difference can be explained by the level of implementation and management of hemodialysis techniques.…”

Section: Resultsmentioning

confidence: 99%

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Outcomes of Hemodialysis Patients in Public Centres in Abidjan from September 2018 to October 2021: Data from the Renal Registry of Cote D'ivoire

Diopoh,

Konan,

Kanganga

et al. 2023

Preprint

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Background : Hemodialysis is the most widely used of renal replacement therapy in developing countries such as Cote d'Ivoire. Objective : To study the outcome of chronic hemodialysis patients in public centres in Abidjan using data from the Renal Registry of Cote d'Ivoire (2RCI). Method : This was a prospective analytical cohort study of End Stage Kidney Disease (ESKD) patients undergoing iterative hemodialysis in the network of public hemodialysis centres in Abidjan and who had been registered in the 2RCI register by September 2018. Results : Our study involved 363 cases out of 379 patients registered in the 2RCI registry database in 2018. The mean age of the patients was 47.3±12.1 years, with a male predominance (sex ratio 1.97). In 70.24% of cases, they had no health insurance. The average duration of dialysis for our patients was 6.94 ± 4.1 years, with extremes of 2 and 28 years. This duration was less than 5 years in 44.3% of cases, between 6 and 10 years in 42.9% and more than 10 years in 12.6% of cases. The comorbidities found were hypertension in 95.6% of cases, diabetes in 7.8% and HIV in 4.6%. Anaemia was found in 68% of cases and stroke in 8.6%. During the study period, 161 deaths were observed, representing a mortality rate of 44.35%. Acute lung oedema (29.8%), stroke (6.8%) and other cardiovascular diseases (19.3%) were the main causes of death. In multivariate analysis, factors such as age ≥ 65 years (HR = 3.66; CI 95% =1.55-8.67; p=0.003), "married/coupled" status (HR = 2.02; CI 95% =1.24-3.31; p=0.005) and normal weight at the start of dialysis (OR = 9.59, CI95% = 4.19-21.95; p=0.001) were associated with the risk of death. Conclusion : Hemodialysis is performed in Abidjan on young patients. The mortality rate after three years of dialysis is very high. Hence the need to pursue the policy of decentralising public centres and optimising access to dialysis in terms of quality and quantity in order to improve patient survival.

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Section: Resultsmentioning

confidence: 99%

“…De ciencies in the quality and quantity of dialysis expose patients to undernutrition. Jean-Philippe reported that cachexia was cause of death for 9% of patients (15).…”

Section: Resultsmentioning

confidence: 99%

Outcomes of Hemodialysis Patients in Public Centres in Abidjan from September 2018 to October 2021: Data from the Renal Registry of Cote D'ivoire

Diopoh,

Konan,

Kanganga

et al. 2023

Preprint

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“…However, despite the many advances in hemodialysis techniques and the decrease in the rate of initiation of emergency hemodialysis, the survival of hemodialysis patients has improved only slightly, and their annual mortality rate remains very high, approaching 16.5% in France in 2021 [ 7 ]. This mortality rate is between 10 times higher, for patients over 60 years old, and 40 times higher, for patients over 90 years old, than that of the general population [ 8 ]. This rate is all the more alarming as it is higher than that of other chronic diseases, making renal failure the 10th leading cause of death worldwide [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

External validation of the 2-year mortality prediction tool in hemodialysis patients developed using a Bayesian network

Granal,

Brokhes-Le Calvez,

Dimitrov

et al. 2024

Clinical Kidney Journal

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Background and hypothesis In recent years, a number of predictive models have appeared to predict the risk of medium-term mortality in haemodialysis patients, but only one, limited to patients aged over 70, has undergone sufficiently powerful external validation. Recently, using a national learning database and an innovative approach based on Bayesian networks and 14 carefully selected predictors, we have developed a clinical prediction tool to predict all-cause mortality at 2 years in all incident haemodialysis patients. In order to generalise the results of this tool and propose its use in routine clinical practice, we carried out an external validation using an independent external validation database. Methods A regional, multicenter, observational, retrospective cohort study was conducted to externally validate the tool for predicting 2-year all-cause mortality in incident and prevalent hemodialysis patients. This study recruited a total of 142 incident and 697 prevalent adult hemodialysis patients followed up in one of the 8 AURAL Alsace dialysis centers. Results In Incident patients, the 2-year all-cause mortality prediction tool had an area under the receiver curve of 0.73, an accuracy of 65%, a sensitivity of 71%, a specificity of 63%. In prevalent patients, the performance for the external validation were similar in terms of AUC-ROC, accuracy, and specificity but was lower in term of sensitivity. Conclusion The tool for predicting all-cause mortality at 2 years, developed using a Bayesian network and 14 routinely available explanatory variables, obtained satisfactory external validation in incident patients, but sensitivity was insufficient in prevalent patients.

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Trajectoires des patients en suppléance

Crémades¹,

Moranne²,

Couchoud³

2022

Néphrologie & Thérapeutique

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Mortalité des patients avec une maladie rénale chronique stade 5 traités par suppléance

Cited by 4 publications

References 1 publication

Outcomes of Hemodialysis Patients in Public Centres in Abidjan from September 2018 to October 2021: Data from the Renal Registry of Cote D'ivoire

Outcomes of Hemodialysis Patients in Public Centres in Abidjan from September 2018 to October 2021: Data from the Renal Registry of Cote D'ivoire

External validation of the 2-year mortality prediction tool in hemodialysis patients developed using a Bayesian network

Trajectoires des patients en suppléance

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