Severe dengue cases have increased in Brazil since 2001, with the first records in
Maranhão dating back to 2002. The aim of this study was to
determine the prevalence of severe dengue cases by age group and the possible risk
factors. This was a study of secondary data on dengue in residents of São
Luís, Maranhão, Brazil, using probable cases notified to the National
Mandatory Reporting System (SINAN) from 2002 to 2011. The diagnosis and
classification of dengue were based on the Brazilian Ministry of Health criteria:
dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue fever with complications
(DWC). DHF and DWC were considered severe dengue, and DF was classified as non-severe
dengue. A logistic regression analysis was performed with severe dengue as the
outcome. During the study period, 1,229 cases of severe dengue were reported; of
these, 812 in patients under the age of 15 (66%). Among the risk factors evaluated,
age under 15 years old (OR = 3.10, 95% CI = 2.69-3.57, p-value = 0.001) was
associated with severe dengue. The prevalence of severe dengue in children under the
age of 15 was higher, and only this age group was associated with the occurrence of
severe dengue.